The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and
the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance …

Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …

Lipopolysaccharide (LPS), a potent endotoxin present in the outer membrane of Gram‑
negative bacteria, causes chronic immune responses associated with inflammation. In the …

Type 2 diabetes mellitus (T2DM) remains one of the most problematic and economic
consumer disorders worldwide, with growing prevalence and incidence. Over the last years …

Oral administration of resveratrol is able to ameliorate the progression of diabetic
nephropathy (DN); however, its mechanisms of action remain unclear. Recent evidence …

Alterations to the gut microbiota have been previously suggested to be tightly linked to
chronic systemic inflammation, which is a major contributing factor to complications and …

Aims The role of probiotics in the management of diabetic kidney disease (DKD) has been
shown. Several current trials are investigating the effect of probiotics, which are widely used …

Diabetes is a metabolic condition. The composition of the gut microbiota is altered in
diabetes with reduced levels of short chain fatty acids (SCFA) producers, notably butyrate …

The incidence of metabolic disorders, including diabetes, has elevated exponentially during
the last decades and enhanced the risk of a variety of complications, such as diabetes and …