Bone marrow mesenchymal stem cells therapy regulates sphingolipid and glycerophospholipid metabolism to promote neurological recovery in stroke rats: A …

S Xu, A Zhong, Y Zhang, L Zhao, Y Guo, X Bai… - Experimental …, 2024 - Elsevier
Bone marrow mesenchymal stem cells (BMSCs) have therapeutic potential in the
subacute/chronic phase of acute ischemic stroke (AIS), but the underlying mechanisms are …

Donor muse cell treatment without HLA-matching tests and immunosuppressant treatment

S Minatoguchi, Y Fujita, K Niizuma… - Stem Cells …, 2024 - academic.oup.com
The strength of stem cell therapy is the regeneration of tissues by synergistic pleiotropic
effects. Among many stem cell types, mesenchymal stem cells (MSCs) that are comprised of …

Mechanism of action of mesenchymal stem cells (MSCs): impact of delivery method

LL Bagno, AG Salerno, W Balkan… - Expert opinion on …, 2022 - Taylor & Francis
ABSTRACT Introduction Mesenchymal stromal cells (MSCs; AKA mesenchymal stem cells)
stimulate healing and reduce inflammation. Promising therapeutic responses are seen in …

[HTML][HTML] BDNF-overexpressing MSCs delivered by hydrogel in acute ischemic stroke treatment

C Wang, C Tian, D Cai, H Jiang, W Zhang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Ischemic stroke treatment is a challenge worldwide. The efficacy and safety of
mesenchymal stem cells (MSCs) for stroke have been confirmed. However, poor survival of …

[HTML][HTML] Mesenchymal stem cell therapy for ischemic stroke: Novel insight into the crosstalk with immune cells

N Tan, W Xin, M Huang, Y Mao - Frontiers in Neurology, 2022 - frontiersin.org
Stroke, a cerebrovascular accident, is prevalent and the second highest cause of death
globally across patient populations; it is as a significant cause of morbidity and mortality …

[HTML][HTML] Exosomes in cerebral ischemia-reperfusion injury: current perspectives and future challenges

C Zhou, F Zhou, Y He, Y Liu, Y Cao - Brain Sciences, 2022 - mdpi.com
Cerebral ischemia impedes the functional or metabolic demands of the central nervous
system (CNS), which subsequently leads to irreversible brain damage. While recanalization …

Preconditioning with trehalose protects the bone marrow-derived mesenchymal stem cells under oxidative stress and enhances the stem cell-based therapy for …

B Shu, J Wan, X Li, R Liu, C Xu, Y An… - Cellular …, 2022 - liebertpub.com
Bone marrow-derived mesenchymal stem cell (BMSC) transplantation has emerged as a
potential treatment for ischemic stroke. Preconditioning with pharmacological agents before …

[HTML][HTML] Optimization of Multimodal Nanoparticles Internalization Process in Mesenchymal Stem Cells for Cell Therapy Studies

MP Nucci, JB Mamani, FA Oliveira, IS Filgueiras… - Pharmaceutics, 2022 - mdpi.com
Considering there are several difficulties and limitations in labeling stem cells using
multifunctional nanoparticles (MFNP), the purpose of this study was to determine the optimal …

[HTML][HTML] To explore the Radix Paeoniae Rubra-Flos Carthami herb pair's potential mechanism in the treatment of ischemic stroke by network pharmacology and …

X Chen, Y Wang, Y Ma, R Wang, D Zhao - Medicine, 2021 - journals.lww.com
To explore the Radix Paeoniae Rubra-Flos Carthami herb pair'... : Medicine To explore the
Radix Paeoniae Rubra-Flos Carthami herb pair's potential mechanism in the treatment of …

[HTML][HTML] Mesenchymal stem cell aggregation mediated by integrin α4/VCAM-1 after intrathecal transplantation in MCAO rats

Y Ran, Y Dong, Y Li, J Xie, S Zeng, C Liang… - Stem Cell Research & …, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have shown immense therapeutic
potential for various brain diseases. Intrathecal administration of MSCs may enhance their …