Therapeutic efficacy and migration of mesenchymal stem cells after intracerebral transplantation in rats with experimental ischemic stroke

DD Namestnikova, IL Gubskiy, EA Cherkashova… - Bulletin of experimental …, 2023 - Springer
We studied therapeutic efficacy and migration characteristics of mesenchymal stem cells
isolated from the human placenta after their intracerebral (stereotactic) administration to rats …

Neural Stem Cell-Derived Small Extracellular Vesicles: key Players in Ischemic Stroke Therapy–A Comprehensive Literature Review

Z Zhu, Q Zhang, J Feng… - International Journal …, 2024 - Taylor & Francis
Ischemic stroke, being a prominent contributor to global disability and mortality, lacks an
efficacious therapeutic approach in current clinical settings. Neural stem cells (NSCs) are a …

Pivotal regulatory roles of traditional Chinese medicine in ischemic stroke via inhibition of NLRP3 inflammasome

YW Tao, L Yang, SY Chen, Y Zhang, Y Zeng… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Many studies have demonstrated the powerful
neuroprotection abilities of multiple traditional Chinese medicines (TCMs) against NLRP3 …

[HTML][HTML] Clinical experience: Outcomes of mesenchymal stem cell transplantation in five stroke patients

N Ercelen, N Karasu, B Kahyaoglu, O Cerezci… - Frontiers in …, 2023 - frontiersin.org
Stem cell therapy, which has promising results in acute disorders such as stroke, supports
treatment by providing rehabilitation in the chronic stage patients. In acute stroke …

Human mesenchymal stromal cells ameliorate cisplatin induced acute and chronic kidney injury via TSG-6

M Tang, L Shen, M Tang, L Liu, Z Rao, Z Wang… - Stem Cells, 2024 - academic.oup.com
Cisplatin is widely employed in tumor chemotherapy, but nephrotoxicity is an unavoidable
side effect of cisplatin. Several studies have demonstrated that mesenchymal stromal cells …

[HTML][HTML] Pre-clinical efficacy evaluation of human umbilical cord mesenchymal stem cells for ischemic stroke

D Shen, H Wang, H Zhu, C Jiang, F Xie… - Frontiers in …, 2023 - frontiersin.org
Objective This study explored the underlying therapeutic mechanism of human umbilical
cord mesenchymal stem cells (hUCMSCs) for ischemic stroke (IS), and determined the …

Therapeutic gene delivery by mesenchymal stem cell for brain ischemia damage: Focus on molecular mechanisms in ischemic stroke

RO Saleh, AA Majeed, R Margiana… - Cell Biochemistry …, 2024 - Wiley Online Library
Cerebral ischemic damage is prevalent and the second highest cause of death globally
across patient populations; it is as a substantial reason of morbidity and mortality …

Update on current and potential application of Extracellular Vesicles (EVs) in Kidney Transplantation

M Abinti, E Favi, CM Alfieri, F Zanoni… - American Journal of …, 2023 - Elsevier
Kidney transplantation (KT) is the best treatment for End-Stage Kidney Disease (ESKD).
However, early diagnosis of graft injury remains challenging, mainly because the lack of …

MicroRNA-124a regulates the differentiation of bone marrow mesenchymal stem cells into neurons

E Zhao, D Wang, L Jing, Z Zhao, S Huang… - Journal of Receptors …, 2023 - Taylor & Francis
Objective This study investigated the effects of microRNA-124a on the differentiation of bone
marrow mesenchymal stem cells (BMSCs) and its underlying mechanism. Methods Flow …

间充质干细胞在变应性鼻炎中的作用研究进展

李文瑾, 王艳杰, 程冯丽, 祁雪萍… - 临床耳鼻咽喉头颈外科 …, 2024 - lceh.whuhzzs.com
变应性鼻炎(allergic rhinitis, AR) 是以上气道高反应为主要特征的鼻黏膜慢性炎症,
涉及多种免疫细胞及炎性介质, 目前以药物, 免疫和手术治疗为主. 研究发现 …