Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7%
of the global population and more than 500 million people worldwide. One research frontier …

Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low
acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …

As pivotal role of scaffold in tissue engineering (TE), the aim of present study was to design
and development of extracellular matrix (ECM)-mimetic electrically conductive nanofibrous …

Osteochondral (OC) defects cannot adequately repair themselves due to their sophisticated
layered structure and lack of blood supply in cartilage. Although therapeutic interventions …

Facile preparation of multifunctional hydrogel wound dressings with inherent versatile
properties is highly desirable in practical healthcare. Here, a biocompatible hydrogel was …

The purpose of cartilage tissue engineering is to provide artificial constructs with biological
functions and mechanical features that resemble native tissue to improve tissue …

Long-standing administration of disease-modifying antirheumatic drugs confirms their
clinical value for managing rheumatoid arthritis (RA). Nevertheless, there are emergent …

Oxygen and reactive oxygen species (ROS), as indispensable small molecular substances
in the basic metabolism of life, have become the key to the success of implantable medical …

Cartilage repair has been a significant challenge in orthopedics that has not yet been fully
resolved. Due to the absence of blood vessels and the almost cell-free nature of mature …

Myocardial infarction (MI) is a significant cardiovascular disease that restricts blood flow,
resulting in massive cell death and leading to stiff and noncontractile fibrotic scar tissue …