• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …

Dilated cardiomyopathy is conventionally defined as the presence of left ventricular or
biventricular dilatation or systolic dysfunction in the absence of abnormal loading conditions …

For years, females were thought of as smaller men with complex hormonal cycles; as a
result, females have been largely excluded from preclinical and clinical research. However …

Transthyretin cardiac amyloidosis (ATTR-CA) is a progressive disease characterized by the
deposition of abnormal transthyretin protein fibrils in the heart, leading to cardiac …

Biological sex is an important modifier of physiology and influences pathobiology in many
diseases. While heart disease is the number one cause of death worldwide in both men and …

Background Biological sex has a diverse impact on the cardiovascular system. Its influence
on dilated cardiomyopathy (DCM) remains unresolved. Objectives This study aims to …

Abstract Purpose of Review Sudden cardiac death (SCD) represents the most feared
complication of heart failure (HF). This review intends to provide insight on our current …

Amyotrophic Lateral Sclerosis (ALS) is a devastating adult-onset neurodegenerative
disease, with ineffective therapeutic options. ALS incidence and prevalence depend on the …

RBM20 cardiomyopathy is an arrhythmogenic form of dilated cardiomyopathy caused by
mutations in the splicing factor RBM20. A recent study found a more severe phenotype in …