Genome-wide association studies have revolutionized our understanding of the genetic
underpinnings of cardiometabolic disease. Yet, the inadequate representation of individuals …

Vietnam features extensive ethnolinguistic diversity and occupies a key position in Mainland
Southeast Asia. Yet, the genetic diversity of Vietnam remains relatively unexplored …

As the largest ethnic group in the world, the Han Chinese population is nonetheless
underrepresented in global efforts to catalogue the genomic variability of natural …

It is known that there has been positive natural selection for hemoglobin S and C in humans
despite negative health effects, due to its role in malaria resistance. However, it is not well …

Given the genomic uniqueness, a local data set is most desired for Indians, who are
underrepresented in existing public databases. We hypothesize patients with rare …

Objective The aim of this study was to investigate risk factors for cutaneous adverse
reactions (CARs) in Kinh Vietnamese. Methods All patients were prospectively recruited in …

Introduction Genetic mutations of PROC and PROS1 are well‐known risk factors for deep
venous thrombosis (DVT) in the Asian population. However, the genetic profile of …

Genome-wide chromosomal microarray is extensively used to detect copy number variations
(CNVs), which can diagnose microdeletion and microduplication syndromes. These small …

Biliary atresia (BA) is a progressive inflammation and fibrosis of the biliary tree characterized
by the obstruction of bile flow, which results in liver failure, scarring and cirrhosis. This study …

A high-quality genome variation database derived from a large-scale population is one of
the most important infrastructures for genomics, clinical and translational medicine research …