Risk of intracranial hemorrhage with direct oral anticoagulants: a systematic review and meta-analysis of randomized controlled trials

T Wu, C Lv, L Wu, W Chen, M Lv, S Jiang, J Zhang - Journal of neurology, 2022 - Springer
Objective We performed a systematic review and meta-analysis to compare the risk of
intracranial hemorrhage (ICH) between direct oral anticoagulants (DOACs) and other …

Advances in the medical treatment and diagnosis of intracranial hemorrhage associated with oral anticoagulation

C Piqueras-Sanchez, MA Esteve-Pastor… - Expert Review of …, 2024 - Taylor & Francis
Introduction With the increasing prevalence of atrial fibrillation (AF), it entails expanding oral
anticoagulants (OACs) use, carrying a higher risk of associated hemorrhagic events …

Factor Xa inhibitors: critical considerations for clinical development and testing

RC Becker - Journal of Thrombosis and Thrombolysis, 2021 - Springer
The selection of factor (F) X and its activated protease FXa for targeted inhibition to prevent
and treat thrombotic conditions is based on an understanding of coagulation biochemistry …

Andexanet alfa to reverse the effect of factor Xa inhibitors in intracranial hemorrhage

S Frol, JP Oblak, M Šabovič, P Kermer - CNS drugs, 2023 - Springer
Andexanet alfa (AA) is a recombinant factor Xa competing for binding with factor Xa
inhibitors, thereby reversing their anticoagulation effects. Since 2019, it has been approved …

[HTML][HTML] Effect of oral anticoagulation therapy in atrial fibrillation patients with a history of intracranial hemorrhage: a systematic review and meta-analysis

M Liu, Y Hou, W Liu, M Liu - Annals of Palliative Medicine, 2022 - apm.amegroups.org
Background: Use of oral anticoagulants (OACs) among atrial fibrillation (AF) patients
surviving intracranial hemorrhage (ICH) represents a challenge due to the difficult balance …

Cierre percutáneo de orejuela izquierda tras hemorragia intracraneal:¿ cuándo realizarlo?

D González Calle - 2022 - gredos.usal.es
[ES] Introducción La anticoagulación oral es el tratamiento por excelencia para la
prevención de eventos embólicos en pacientes con fibrilación auricular, arritmia cardiaca …