Sleep disturbance, sleep disorders and co-morbidities in the care of the older person

CE Mc Carthy - Medical Sciences, 2021 - mdpi.com
Sleep complaints can be both common and complex in the older patient. Their consideration
is an important aspect of holistic care, and may have an impact on quality of life, mortality …

Impact of hypoxia on male reproductive functions

PA Oyedokun, RE Akhigbe, LO Ajayi… - Molecular and Cellular …, 2023 - Springer
Male reproductive functions, which include testicular steroidogenesis, spermatogenesis, and
sexual/erectile functions are key in male fertility, but may be adversely altered by several …

Associations between physical multimorbidity patterns and common mental health disorders in middle-aged adults: A prospective analysis using data from the UK …

A Ronaldson, JA de la Torre, M Prina… - The Lancet Regional …, 2021 - thelancet.com
Background We aimed to identify specific patterns of physical multimorbidity, defined as the
presence of two or more physical long-term conditions, and to examine the extent to which …

[HTML][HTML] Mortality in obstructive sleep apnea syndrome (OSAS) and overlap syndrome (OS): The role of nocturnal hypoxemia and CPAP compliance

P Tondo, G Scioscia, R Sabato, R Leccisotti… - Sleep Medicine, 2023 - Elsevier
Background Obstructive sleep apnea syndrome (OSAS) and chronic obstructive pulmonary
disease (COPD) are two chronic diseases that afflict many individuals worldwide with …

Contemporary perspectives in COPD: patient burden, the role of gender and trajectories of multimorbidity

SC Buttery, M Zysman, SAA Vikjord… - …, 2021 - Wiley Online Library
An individual's experience of COPD is determined by many factors in addition to the
pathological features of chronic bronchitis and emphysema and the symptoms that derive …

The PI3K/AKT/mTOR pathway regulates autophagy to induce apoptosis of alveolar epithelial cells in chronic obstructive pulmonary disease caused by PM2. 5 …

F Zhang, H Ma, ZL Wang, WH Li… - Journal of …, 2020 - journals.sagepub.com
Objective Many lung diseases are associated with changes in autophagic activity. The
phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin …

Overlaps between obstructive sleep apnoea and other respiratory diseases, including COPD, asthma and interstitial lung disease

I Bouloukaki, M Fanaridis, D Testelmans, A Pataka… - Breathe, 2022 - Eur Respiratory Soc
In the past, there was limited research relating to the role of sleep in respiratory diseases.
Physicians treating these patients tended to focus mainly on the daily disabling symptoms …

Prevalence and clinical characteristics of sleep disorders in chronic obstructive pulmonary disease: A systematic review and meta-analysis

D Du, G Zhang, D Xu, L Liu, X Hu, L Chen, X Li, Y Shen… - Sleep Medicine, 2023 - Elsevier
Background Sleep disorders, including obstructive sleep apnea (OSA), restless leg
syndrome (RLS) and insomnia, are present in chronic obstructive pulmonary disease …

Extra-pulmonary manifestations of COPD and the role of pulmonary rehabilitation: a symptom-centered approach

A Machado, A Marques, C Burtin - Expert review of respiratory …, 2021 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is a complex and
heterogenous disease that is associated with a range of respiratory and non-respiratory …

Sleep and cardiometabolic comorbidities in the obstructive sleep apnoea–COPD overlap syndrome: data from the European Sleep Apnoea Database

M van Zeller, OK Basoglu, J Verbraecken… - ERJ open …, 2023 - Eur Respiratory Soc
Aim The impact of obstructive sleep apnoea (OSA)–COPD overlap syndrome (OVS) on
sleep quality and cardiovascular outcomes has not been fully explored. We aimed to …