Locoregional therapies in the era of molecular and immune treatments for hepatocellular carcinoma

JM Llovet, T De Baere, L Kulik, PK Haber… - Nature reviews …, 2021 - nature.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality and
has an increasing incidence worldwide. Locoregional therapies, defined as imaging-guided …

Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma

PR Galle, F Foerster, M Kudo, SL Chan… - Liver …, 2019 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer‐related
deaths globally due, in part, to the majority of patients being diagnosed with intermediate or …

EASL clinical practice guidelines: management of hepatocellular carcinoma

PR Galle, A Forner, JM Llovet, V Mazzaferro… - Journal of …, 2018 - Elsevier
Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …

METTL1 promotes hepatocarcinogenesis via m7G tRNA modification‐dependent translation control

Z Chen, W Zhu, S Zhu, K Sun, J Liao… - Clinical and …, 2021 - Wiley Online Library
Abstract Background N7‐methylguanosine (m7G) modification is one of the most common
transfer RNA (tRNA) modifications in humans. The precise function and molecular …

Percutaneous treatment of hepatocellular carcinoma: state of the art and innovations

JC Nault, O Sutter, P Nahon, N Ganne-Carrié… - Journal of …, 2018 - Elsevier
Percutaneous treatment of hepatocellular carcinoma (HCC) encompasses a vast range of
techniques, including monopolar radiofrequency ablation (RFA), multibipolar RFA …

Ultrasound-guided radiofrequency ablation versus surgery for low-risk papillary thyroid microcarcinoma: results of over 5 years' follow-up

M Zhang, RP Tufano, JO Russell, Y Zhang, Y Zhang… - Thyroid, 2020 - liebertpub.com
Background: Papillary thyroid microcarcinoma (PTMC) typically carries an excellent
prognosis regardless of the treatment option pursued. Radiofrequency ablation (RFA) for …

[HTML][HTML] Cancer and liver cirrhosis: implications on prognosis and management

M Pinter, M Trauner, M Peck-Radosavljevic, W Sieghart - ESMO open, 2016 - Elsevier
Liver cirrhosis, the end-stage of every chronic liver disease, is not only the major risk factor
for the development of hepatocellular carcinoma but also a limiting factor for anticancer …

[HTML][HTML] Blood biomarkers predict outcomes in patients with hepatocellular carcinoma treated with immune checkpoint Inhibitors: A pooled analysis of 44 retrospective …

L Zhang, J Feng, T Kuang, D Chai, Z Qiu… - International …, 2023 - Elsevier
Objective We conducted the first meta-analysis to identify the predictive significance of
baseline blood biomarkers (such as neutrophil to lymphocyte ratio (NLR), early alpha …

Insufficient radiofrequency ablation promotes hepatocellular carcinoma metastasis through N6‐methyladenosine mRNA methylation‐dependent mechanism

T Su, M Huang, J Liao, S Lin, P Yu, J Yang, Y Cai… - …, 2021 - Wiley Online Library
Background and Aims The dynamic N6‐methyladenosine (m6A) mRNA modification is
essential for acute stress response and cancer progression. Sublethal heat stress from …

Prognostic impact of C-reactive protein and alpha-fetoprotein in immunotherapy score in hepatocellular carcinoma patients treated with atezolizumab plus …

T Hatanaka, S Kakizaki, A Hiraoka, T Tada… - Hepatology …, 2022 - Springer
Aim This study aimed to investigate the utility of C-reactive protein (CRP) and alpha-
fetoprotein (AFP) in immunotherapy (CRAFITY) score in hepatocellular carcinoma (HCC) …