Representational drift as a window into neural and behavioural plasticity
Large-scale recordings of neural activity over days and weeks have revealed that neural
representations of familiar tasks, precepts and actions continually evolve without obvious …
representations of familiar tasks, precepts and actions continually evolve without obvious …
Time and experience differentially affect distinct aspects of hippocampal representational drift
Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …
[HTML][HTML] Representational drift in the mouse visual cortex
Recent studies have shown that neuronal representations gradually change over time
despite no changes in the stimulus, environment, or behavior. However, such …
despite no changes in the stimulus, environment, or behavior. However, such …
Drifting neuronal representations: Bug or feature?
The brain displays a remarkable ability to sustain stable memories, allowing animals to
execute precise behaviors or recall stimulus associations years after they were first learned …
execute precise behaviors or recall stimulus associations years after they were first learned …
[HTML][HTML] Hippocampal place codes are gated by behavioral engagement
As animals explore an environment, the hippocampus is thought to automatically form and
maintain a place code by combining sensory and self-motion signals. Instead, we observed …
maintain a place code by combining sensory and self-motion signals. Instead, we observed …
Spatial information encoding across multiple neocortical regions depends on an intact hippocampus
IM Esteves, HR Chang, AR Neumann… - Journal of …, 2021 - Soc Neuroscience
There has been considerable research showing populations of neurons encoding for
different aspects of space in the brain. Recently, several studies using two-photon calcium …
different aspects of space in the brain. Recently, several studies using two-photon calcium …
Functional network topography of the medial entorhinal cortex
The medial entorhinal cortex (MEC) creates a map of local space, based on the firing
patterns of grid, head-direction (HD), border, and object-vector (OV) cells. How these cell …
patterns of grid, head-direction (HD), border, and object-vector (OV) cells. How these cell …
[HTML][HTML] Organization of hippocampal CA3 into correlated cell assemblies supports a stable spatial code
Hippocampal subfield CA3 is thought to stably store memories in assemblies of recurrently
connected cells functioning as a collective. However, the collective hippocampal coding …
connected cells functioning as a collective. However, the collective hippocampal coding …
In vivo multi-day calcium imaging of CA1 hippocampus in freely moving rats reveals a high preponderance of place cells with consistent place fields
HS Wirtshafter, JF Disterhoft - Journal of Neuroscience, 2022 - Soc Neuroscience
Calcium imaging using GCaMP indicators and miniature microscopes has been used to
image cellular populations during long timescales and in different task phases, as well as to …
image cellular populations during long timescales and in different task phases, as well as to …
Neural ensembles in navigation: From single cells to population codes
EAA Jones, LM Giocomo - Current opinion in neurobiology, 2023 - Elsevier
The brain can represent behaviorally relevant information through the firing of individual
neurons as well as the coordinated firing of ensembles of neurons. Neurons in the …
neurons as well as the coordinated firing of ensembles of neurons. Neurons in the …