Representational drift as a window into neural and behavioural plasticity

C Micou, T O'Leary - Current opinion in neurobiology, 2023 - Elsevier
Large-scale recordings of neural activity over days and weeks have revealed that neural
representations of familiar tasks, precepts and actions continually evolve without obvious …

Time and experience differentially affect distinct aspects of hippocampal representational drift

N Geva, D Deitch, A Rubin, Y Ziv - Neuron, 2023 - cell.com
Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …

[HTML][HTML] Representational drift in the mouse visual cortex

D Deitch, A Rubin, Y Ziv - Current biology, 2021 - cell.com
Recent studies have shown that neuronal representations gradually change over time
despite no changes in the stimulus, environment, or behavior. However, such …

Drifting neuronal representations: Bug or feature?

P Masset, S Qin, JA Zavatone-Veth - Biological cybernetics, 2022 - Springer
The brain displays a remarkable ability to sustain stable memories, allowing animals to
execute precise behaviors or recall stimulus associations years after they were first learned …

[HTML][HTML] Hippocampal place codes are gated by behavioral engagement

NL Pettit, XC Yuan, CD Harvey - Nature neuroscience, 2022 - nature.com
As animals explore an environment, the hippocampus is thought to automatically form and
maintain a place code by combining sensory and self-motion signals. Instead, we observed …

Spatial information encoding across multiple neocortical regions depends on an intact hippocampus

IM Esteves, HR Chang, AR Neumann… - Journal of …, 2021 - Soc Neuroscience
There has been considerable research showing populations of neurons encoding for
different aspects of space in the brain. Recently, several studies using two-photon calcium …

Functional network topography of the medial entorhinal cortex

HA Obenhaus, W Zong, RI Jacobsen… - Proceedings of the …, 2022 - National Acad Sciences
The medial entorhinal cortex (MEC) creates a map of local space, based on the firing
patterns of grid, head-direction (HD), border, and object-vector (OV) cells. How these cell …

[HTML][HTML] Organization of hippocampal CA3 into correlated cell assemblies supports a stable spatial code

L Sheintuch, N Geva, D Deitch, A Rubin, Y Ziv - Cell reports, 2023 - cell.com
Hippocampal subfield CA3 is thought to stably store memories in assemblies of recurrently
connected cells functioning as a collective. However, the collective hippocampal coding …

In vivo multi-day calcium imaging of CA1 hippocampus in freely moving rats reveals a high preponderance of place cells with consistent place fields

HS Wirtshafter, JF Disterhoft - Journal of Neuroscience, 2022 - Soc Neuroscience
Calcium imaging using GCaMP indicators and miniature microscopes has been used to
image cellular populations during long timescales and in different task phases, as well as to …

Neural ensembles in navigation: From single cells to population codes

EAA Jones, LM Giocomo - Current opinion in neurobiology, 2023 - Elsevier
The brain can represent behaviorally relevant information through the firing of individual
neurons as well as the coordinated firing of ensembles of neurons. Neurons in the …