Dry Powder Inhaler with the technical and practical obstacles, and forthcoming platform strategies
SS Gaikwad, SR Pathare, MA More… - Journal of Controlled …, 2023 - Elsevier
Abstract A Dry Powder Inhaler (DPI) is a technique as well as a device used to inhale
formulation which is in the form of dry powder, and is inhaled through the nose or mouth. It …
formulation which is in the form of dry powder, and is inhaled through the nose or mouth. It …
A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications
HI Shahin, L Chablani - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …
delivery. However, designing DPIs with adequate physicochemical properties is …
An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models
The Omicron variant continuously evolves under the humoral immune pressure exerted by
vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
Ranking the risks of eighty pharmaceuticals in surface water of a megacity: A multilevel optimization strategy
Pharmaceuticals in freshwater posed ecological risks to aquatic ecosystem, however, most
risk assessments of pharmaceuticals were conducted at screening level, which were limited …
risk assessments of pharmaceuticals were conducted at screening level, which were limited …
Inhalation of vaccines and antiviral drugs to fight respiratory virus infections: reasons to prioritize the pulmonary route of administration
Many of the current pandemic threats are caused by viruses that infect the respiratory tract.
Remarkably though, the majority of vaccines and antiviral drugs are administered via …
Remarkably though, the majority of vaccines and antiviral drugs are administered via …
Treatment of respiratory viral infections through inhalation therapeutics: Challenges and opportunities
N Nainwal - Pulmonary Pharmacology & Therapeutics, 2022 - Elsevier
Respiratory viral infections are the leading cause of death worldwide. The current pandemic
of coronavirus infection (COVID-19) challenged human beings for the treatment and …
of coronavirus infection (COVID-19) challenged human beings for the treatment and …
Pulmonary delivery of favipiravir inhalation solution for COVID-19 treatment: in vitro characterization, stability, in vitro cytotoxicity, and antiviral activity using real time …
A Yildiz Pekoz, O Akbal Dagistan, H Fael, M Culha… - Drug Delivery, 2022 - Taylor & Francis
Favipiravir, an RNA-dependent RNA polymerase (RdRp) inhibitor, is used to treat patients
infected with influenza virus and most recently with SARS-CoV-2. However, poor …
infected with influenza virus and most recently with SARS-CoV-2. However, poor …
Potential of green tea EGCG in neutralizing SARS-CoV-2 Omicron variant with greater tropism toward the upper respiratory tract
Z Zhang, M Hao, X Zhang, Y He, X Chen… - Trends in Food Science …, 2023 - Elsevier
Background COVID-19 due to SARS-CoV-2 infection has had an enormous adverse impact
on global public health. As the COVID-19 pandemic evolves, the WHO declared several …
on global public health. As the COVID-19 pandemic evolves, the WHO declared several …
Dopamine and its precursor levodopa inactivate SARS-CoV-2 main protease by forming a quinoprotein
M Hao, Y He, T Song, H Guo, MP Rayman… - Free Radical Biology and …, 2024 - Elsevier
Many studies show either the absence, or very low levels of, SARS-CoV-2 viral RNA and/or
antigen in the brain of COVID-19 patients. Reports consistently indicate an abortive infection …
antigen in the brain of COVID-19 patients. Reports consistently indicate an abortive infection …
Strictinin, a major ingredient in Yunnan kucha tea possessing inhibitory activity on the infection of mouse hepatitis virus to mouse L cells
EC Tu, WL Hsu, JTC Tzen - Molecules, 2023 - mdpi.com
Theacrine and strictinin of Yunnan Kucha tea prepared from a mutant variety of wild Pu'er
tea plants were two major ingredients responsible for the anti-influenza activity. As the …
tea plants were two major ingredients responsible for the anti-influenza activity. As the …