Intranasal COVID-19 vaccines: From bench to bed

A Alu, L Chen, H Lei, Y Wei, X Tian, X Wei - EBioMedicine, 2022 - thelancet.com
Currently licensed COVID-19 vaccines are all designed for intramuscular (IM) immunization.
However, vaccination today failed to prevent the virus infection through the upper respiratory …

[HTML][HTML] Novel approaches for vaccine development

MS Gebre, LA Brito, LH Tostanoski, DK Edwards… - Cell, 2021 - cell.com
Vaccines are critical tools for maintaining global health. Traditional vaccine technologies
have been used across a wide range of bacterial and viral pathogens, yet there are a …

Emerging concepts and technologies in vaccine development

M Brisse, SM Vrba, N Kirk, Y Liang, H Ly - Frontiers in immunology, 2020 - frontiersin.org
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused
by pathogens, there are still known diseases and emerging pathogens for which the …

COVID-19 and cancer: From basic mechanisms to vaccine development using nanotechnology

HJ Han, C Nwagwu, O Anyim, C Ekweremadu… - International …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic which has induced …

Current state and challenges in developing oral vaccines

JEV Ramirez, LA Sharpe, NA Peppas - Advanced drug delivery reviews, 2017 - Elsevier
While vaccination remains the most cost effective strategy for disease prevention,
communicable diseases persist as the second leading cause of death worldwide. There is a …

Platforms for production of protein-based vaccines: from classical to next-generation strategies

R Cid, J Bolívar - Biomolecules, 2021 - mdpi.com
To date, vaccination has become one of the most effective strategies to control and reduce
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …

Advances in infectious disease vaccine adjuvants

J Fan, S Jin, L Gilmartin, I Toth, WM Hussein… - Vaccines, 2022 - mdpi.com
Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …

The early landscape of coronavirus disease 2019 vaccine development in the UK and rest of the world

HR Sharpe, C Gilbride, E Allen… - …, 2020 - Wiley Online Library
Summary Since the first World Health Organization notification on 31 December 2019,
coronavirus disease 2019 (COVID‐19), the respiratory disease caused by the coronavirus …

Functionalizing ferritin nanoparticles for vaccine development

MQ Rodrigues, PM Alves, A Roldão - Pharmaceutics, 2021 - mdpi.com
In the last decade, the interest in ferritin-based vaccines has been increasing due to their
safety and immunogenicity. Candidates against a wide range of pathogens are now on …

[HTML][HTML] Fungal vaccines, mechanism of actions and immunology: A comprehensive review

S Nami, R Mohammadi, M Vakili, K Khezripour… - Biomedicine & …, 2019 - Elsevier
Fungal infections include a wide range of opportunistic and invasive diseases. Two of four
major fatal diseases in patients with human immunodeficiency virus (HIV) infection are …