Epidemiology of testicular cancer: an overview

MJ Garner, MC Turner, P Ghadirian… - International journal of …, 2005 - Wiley Online Library
Testicular cancer is a rare disease, accounting for 1.1% of all malignant neoplasms in
Canadian males. Despite the low overall incidence of testicular cancer, it is the most …

An overview of testicular germ cell tumors

A Bahrami, JY Ro, AG Ayala - Archives of pathology & …, 2007 - meridian.allenpress.com
Abstract Context.—More than 90% of testicular neoplasms originate from germ cells.
Testicular germ cell tumors (GCTs) are a heterogeneous group of neoplasms with diverse …

Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists

J Lobo, AL Costa, B Vilela-Salgueiro, A Rodrigues… - Human pathology, 2018 - Elsevier
Testicular germ cell tumors (TGCTs) are strikingly heterogeneous, reflecting a complex
tumor model, posing serious challenges for pathologists. Accurate classification and staging …

[HTML][HTML] MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

M Rossi, D Colecchia, G Ilardi, M Acunzo, G Nigita… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Germ cell tumors (GCT) are the most common malignancies in males between 15 and 35
years of age. Despite the high cure rate, achieved through chemotherapy and/or surgery, the …

“Off-label” usage of testicular self-examination (TSE): benefits beyond cancer detection

MJ Rovito, JE Leone… - American journal of …, 2018 - journals.sagepub.com
Testicular cancer (TCa) is the most common cancer among 15-to 34-year-old males.
Treatments are highly effective, which help foster approximately 98% 5-year survival rate …

Molecular and cell biology of testicular germ cell tumors

P Chieffi, R Franco, G Portella - International review of cell and molecular …, 2009 - Elsevier
Although testicular germ cell tumors (TGCTs) are relatively uncommon, they are particularly
important as they tend to affect children and young men, representing the most common …

Sarcomatoid yolk sac tumor harbors somatic mutations that are otherwise rare in testicular germ cell tumors

AM Acosta, KI Al-Obaidy, LM Sholl… - The American Journal …, 2022 - journals.lww.com
In testicular germ cell tumors (TGCTs), components with nonspecific sarcomatous features
that express keratins and glypican 3 are classified as sarcomatoid yolk sac tumor (SYST) …

Percentage of teratoma in orchiectomy and risk of retroperitoneal teratoma at the time of postchemotherapy retroperitoneal lymph node dissection in germ cell tumors

AC Calaway, SQ Kern, D Crook, Y Tong… - The Journal of …, 2021 - auajournals.org
Purpose: Presence of teratoma in the orchiectomy and residual retroperitoneal mass size
are known predictors of finding teratoma during postchemotherapy retroperitoneal lymph …

Risk factors for testicular cancer–differences between pure non‐seminoma and mixed seminoma/non‐seminoma?

EL Aschim, TB Haugen, S Tretli… - … journal of andrology, 2006 - Wiley Online Library
The origin of testicular germ cell cancer (TGCC) is believed to be carcinoma in situ cells
developed in utero. Clinically, TGCCs are divided into two major histological groups …

Salvage chemotherapy with methotrexate, etoposide and actinomycin D in men with metastatic nonseminomatous germ cell tumors with a choriocarcinoma …

T Terakawa, H Miyake, M Muramaki… - … journal of urology, 2010 - Wiley Online Library
The objective of the present study was to assess the use of salvage chemotherapy using
methotrexate, etoposide and actinomycin D (MEA) in men with nonseminomatous germ cell …