Progress in the treatment of drug-induced liver injury with natural products

Y Sun, Y Zhang, L Xie, F Rong, X Zhu, J Xie… - Pharmacological …, 2022 - Elsevier
There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …

Hepatoprotective effects of walnut oil and Caralluma tuberculata against paracetamol in experimentally induced liver toxicity in mice

S ur Rahman, M Zahid, AA Khan, T Aziz… - Acta Biochimica …, 2022 - abp.ptbioch.edu.pl
Abstract Walnut Oil and Caralluma are edible and form part of the traditional medicine
system in many countries. These are frequently used in traditional medicine as remedies to …

A novel water-soluble chitosan grafted with nerol: Synthesis, characterization and biological activity

F Yang, L Chen, D Zhao, T Guo, D Yu, X Zhang… - International Journal of …, 2023 - Elsevier
In order to improve the antibacterial activity of chitosan and change its solubility, a novel
water-soluble chitosan (CS)-nerol (N) derivative (CS-N) was prepared via Schiff base …

[HTML][HTML] Cytotoxic and antioxidant properties of natural bioactive monoterpenes nerol, estragole, and 3, 7-dimethyl-1-octanol

ML Coêlho, MT Islam, GL da Silva Oliveira… - Advances in …, 2022 - ncbi.nlm.nih.gov
The therapeutic potential of medicinal plants is noted because of the presence of varieties of
biochemicals. The monoterpenes, like nerol, estragole, and 3, 7-dimethyl-1-octanol, have …

GC–MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive …

C Sarkar, M Mondal, K Al-Khafaji, DM El-Kersh… - Life Sciences, 2022 - Elsevier
The present study attempted to scrutinize the protective effect of the methanolic extract of P.
chaba stem bark against paracetamol-induced hepatotoxicity in Sprague− Dawley rats …

[HTML][HTML] Discrimination and characterization of the volatile organic compounds of Acori tatarinowii rhizoma based on headspace-gas chromatography-ion mobility …

X Wu, W Li, C Li, J Yin, T Wu, M Zhang, L Zhu… - Arabian Journal of …, 2022 - Elsevier
Acori tatarinowii rhizome (ATR) is a Traditional Chinese Medicine (TCM), which has multiple
effects, such as neuroprotective activity, antidepressant and other activity. However, the …

Therapeutic potential of isorhamnetin following acetaminophen-induced hepatotoxicity through targeting NLRP3/NF-κB/Nrf2

AM Rousta, A Shahmohammadi, Z Mehrabi… - Drug …, 2022 - thieme-connect.com
Acetaminophen (APAP)-induced acute liver injury (ALI) is the principal cause of acute liver
failure (ALF) in some countries including the United States and with few available …

Caesalpinia bonducella Counteracts Paracetamol-Instigated Hepatic Toxicity via Modulating TNF-α and IL-6/10 Expression and Bcl-2 and Caspase-8/3 Signalling

S Nithiyanandam, SE Prince - Applied Biochemistry and Biotechnology, 2023 - Springer
Paracetamol is the most predominantly used antipyretic and analgesic drug. As paracetamol
is metabolised mostly in the liver, both deliberate and unintentional overdoses of …

Sinapic acid ameliorates paracetamol-induced acute liver injury through targeting oxidative stress and inflammation

A Rostami, T Baluchnejadmojarad… - Molecular Biology Reports, 2022 - Springer
Background Acetaminophen (paracetamol, APAP) overdose is the principal cause of acute
liver injury (ALI) that leads to liver failure typified with oxidative stress, mitochondrial and …

[HTML][HTML] Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats

MS Abduh, SAM Saghir, NA Al-Gabri… - Saudi journal of …, 2023 - Elsevier
Paracetamol (PAR) is a commonly used antipyretic and analgesic agent, but its excessive
usage can induce liver damage and major health consequences. Interleukin-35 (IL-35) is …