Alzheimer's disease (AD) is the most common neurodegenerative disorder where the
accumulation of amyloid plaques and the formation of tau tangles are the prominent …

Amino acids are the building blocks of protein, but also play important cellular signaling
roles. The mechanisms through which altered levels of many amino acids are sensed and …

Increasing evidence suggests Alzheimer's disease (AD) pathophysiology is influenced by
primary and secondary bile acids, the end product of cholesterol metabolism. We analyze …

Background Metabolic alterations, related to cerebral glucose metabolism, brain insulin
resistance, and age-induced mitochondrial dysfunction, play an important role in Alzheimer's …

Background Alzheimer's disease (AD) is associated with metabolic abnormalities linked to
critical elements of neurodegeneration. We recently administered combined metabolic …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the …

Healthy aging is an ambitious aspiration for humans, but neurodegenerative disorders, such
as Alzheimer's disease (AD), strongly affect quality of life. Using an integrated omics …

Oxidative and nitrosative stress are widely recognized as critical factors in the pathogenesis
and progression of Alzheimer disease (AD) and its earlier stage, amnestic mild cognitive …

After fecal microbiota transplantation (FMT) to treat Clostridioides difficile infection (CDI),
cognitive improvement is noticeable, suggesting an essential association between the gut …

Accurate identification of Alzheimer's disease (AD) is still of major clinical importance
considering the current lack of noninvasive and low-cost diagnostic approaches. Detection …