A substantial number of studies have reported the development of gene expression–based
prognostic signatures for lung cancer. The ultimate aim of such studies should be the …

Circulating tumour cells (CTCs) have attracted much recent interest in cancer research as a
potential biomarker and as a means of studying the process of metastasis. It has long been …

Introduction Pathological examination of histopathological slides is a routine clinical
procedure for lung cancer diagnosis and prognosis. Although the classification of lung …

Objective To define the anatomic extent of visceral pleural invasion (VPI) and to assess
whether elastic stains are useful to determine VPI in lung cancer. The elastic layer of the …

Chromosomal imbalances resulting in altered gene dosage play a role in the molecular
pathogenesis of non–small cell lung cancer (NSCLC), but the target genes remain to be …

Resectable non-small-cell lung cancer (NSCLC) patients have poor prognosis, with 30–50%
relapsing within 5 years. Current staging criteria do not fully capture the complexity of this …

Purpose: The requirement of frozen tissues for microarray experiments limits the clinical
usage of genome-wide expression profiling by using microarray technology. The goal of this …

Background Surgical outcomes of early-stage non-small cell lung cancer (NSCLC) are poor.
The Geriatric Nutritional Risk Index (GNRI) is a useful parameter for evaluating nutritional …

Purpose: New prognostic markers to guide treatment decisions in early stage non–small cell
lung cancer are necessary to improve patient outcomes. In this report, we assess the utility of …

Lung cancer is the leading cause of cancer mortality worldwide, resulting in 88% deaths of
all diagnosed patients. Hence, novel therapeutic modalities are urgently needed. Single …