Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Biotechnological monoclonal antibodies and receptor antagonists capable of targeting
specific inflammatory actors, such as cytokines, cytokines receptors, co-stimulatory …

Psoriasis is a common, chronic skin disease that results mainly from the complex interplay
between T cells, dendritic cells, and inflammatory cytokines including TNF-α, IL-17, IL-12 …

TNF signals via two receptors, TNFR1 and TNFR2, which play contrasting roles in immunity.
Most of the pro-inflammatory effects of TNF are mediated by TNFR1, whereas TNFR2 is …

Introduction Psoriasis is a common, chronic immune-mediated skin disease frequently
associated to inflammatory and metabolic comorbidities. About 20–30% of patients are …

Hidradenitis suppurativa (HS) as a paradoxical adverse event (PAE) from using anti-
interleukin (IL)-1 has not been reported in the literature, to our knowledge. We herein report …

Objectives The objectives of this study were to assess the clinical characteristics, predictive
factors, and practical algorithms of paradoxical reactions (PRs), specifically paradoxical …

Psoriasis is a chronic recurrent inflammatory autoimmune pathology with a significant
genetic component and several interferences of immunological cells and their cytokines …

Dear Editor, We read with great interest the paper by Papi et al. reporting a case of ocular
myasthenia gravis (MG) in a patient with chronic plaque psoriasis who received …

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPho) syndrome is a rare
autoinflammatory disorder disease characterized by skin lesions and osteoarticular …