Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …

Human induced pluripotent stem cells (hiPSCs) provide a powerful platform for disease
modeling and have unlocked new possibilities for understanding the mechanisms governing …

Extracellular matrix (ECM) plays an important developmental role by regulating cell
behaviour through structural and biochemical stimulation. Tissue-specific ECM, attained …

Discarded human donor organs have been shown to provide decellularized extracellular
matrix (dECM) scaffolds suitable for organ engineering. The quest for appropriate cell …

Transplantation is the only curative treatment option available for patients suffering from end‐
stage organ failure, improving their quality of life and long‐term survival. However, because …

Technical progress in materials science and bioprinting has for the past few decades
fostered considerable advances in medicine. More recently, the understanding of the …

All tissues are surrounded by a mixture of noncellular matrix components, that not only
provide physical and mechanical support to cells, but also mediate biochemical signaling …

Tissue engineering (TE) offers a potential solution for the shortage of transplantable organs
and the need for novel methods of tissue repair. Methods of TE have advanced significantly …

Natural extracellular matrices (ECM) are currently being studied as an alternative source for
organ transplantation or as new solutions to treat kidney injuries, which can evolve to end …

The kidneys are often involved in adverse effects and toxicity caused by exposure to foreign
compounds, chemicals, and drugs. Early predictions of these influences are essential to …