Potential involvement of the extracranial venous system in central nervous system disorders and aging

R Zivadinov, CP Chung - BMC medicine, 2013 - Springer
Background The role of the extracranial venous system in the pathology of central nervous
system (CNS) disorders and aging is largely unknown. It is acknowledged that the …

Autonomic dysregulation in multiple sclerosis

A Pintér, D Cseh, A Sárközi, BM Illigens… - International Journal of …, 2015 - mdpi.com
Multiple sclerosis (MS) is a chronic, progressive central neurological disease characterized
by inflammation and demyelination. In patients with MS, dysregulation of the autonomic …

Efficacy and safety of extracranial vein angioplasty in multiple sclerosis: a randomized clinical trial

P Zamboni, L Tesio, S Galimberti, L Massacesi… - JAMA …, 2018 - jamanetwork.com
Importance Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
restricted venous outflow from the brain and spinal cord. Whether this condition is …

The role of noninvasive and invasive diagnostic imaging techniques for detection of extra-cranial venous system anomalies and developmental variants

K Dolic, AH Siddiqui, Y Karmon, K Marr, R Zivadinov - BMC medicine, 2013 - Springer
The extra-cranial venous system is complex and not well studied in comparison to the
peripheral venous system. A newly proposed vascular condition, named chronic …

Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study

G Comi, MA Battaglia, A Bertolotto… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a
possible cause of multiple sclerosis (MS). Objectives: The CoSMo study evaluated the …

Meta-analysis of the correlation between chronic cerebrospinal venous insufficiency and multiple sclerosis

BA Zwischenberger, MM Beasley… - Vascular and …, 2013 - journals.sagepub.com
Purpose: To determine whether a correlation exists between chronic cerebrospinal venous
insufficiency (CCSVI) and multiple sclerosis (MS). Materials and Methods: A meta-analysis …

Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study

IW Rodger, D Dilar, J Dwyer, J Bienenstock, A Coret… - PLoS …, 2013 - journals.plos.org
Objective Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS.
Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous …

Variability in the cross-sectional area and narrowing of the internal jugular vein in patients without multiple sclerosis

K Buch, R Groller, RN Nadgir, A Fujita… - American Journal of …, 2016 - Am Roentgen Ray Soc
OBJECTIVE. Chronic cerebrospinal vascular insufficiency is a proposed condition of
intraluminal stenosis of the internal jugular vein (IJV) that impedes venous flow from the …

Internal jugular and vertebral vein volume flow in patients with clinically isolated syndrome or mild multiple sclerosis and healthy controls: results from a prospective …

B Chambers, J Chambers, L Churilov… - …, 2014 - journals.sagepub.com
Objectives & Methods: We evaluated internal jugular vein and vertebral vein volume flow
using ultrasound, in patients with clinically isolated syndrome or mild multiple sclerosis and …

Lack of correlation between extracranial venous abnormalities and multiple sclerosis: a quantitative MRI study

S Cocozza, A Canna, R Lanzillo… - The British journal of …, 2016 - academic.oup.com
Objective: We aimed to evaluate the presence of venous stenosis and blood flow
abnormalities in the neck vessels of patients with multiple sclerosis (MS), in respect to a …