Stemness combines the ability of a cell to perpetuate its lineage, to give rise to differentiated
cells, and to interact with its environment to maintain a balance between quiescence …

Junctional adhesion molecules (JAM)-A,-B and-C are cell-cell adhesion molecules of the
immunoglobulin superfamily which are expressed by a variety of tissues, both during …

With the 13th edition, Wintrobe's Clinical Hematology once again bridges the gap between
the clinical practice of hematology and the basic foundations of science. Broken down into …

Therapy resistance represents a major clinical challenge in acute myeloid leukemia (AML).
Here we define a 'MitoScore'signature, which identifies high mitochondrial oxidative …

The adoption of Warburg metabolism is critical for the activation of macrophages in
response to lipopolysaccharide. Macrophages stimulated with lipopolysaccharide increase …

Hematopoietic stem and progenitor cells (HSPCs) are considered as a heterogeneous
population, but precisely when, where and how HSPC heterogeneity arises remain largely …

Embryonic hematopoietic stem and progenitor cells (HSPCs) robustly proliferate while
maintaining multilineage potential in vivo; however, an incomplete understanding of …

Hematopoietic stem cells (HSCs) produce all lineages of mature blood cells for the lifetime
of an organism. In vertebrates, HSCs derive from the transition of the hemogenic …

De novo generation of haematopoietic stem cells from different human pluripotent stem cell
sources remains a high priority for haematology and regenerative medicine. At present …

Advances in understanding how cancer cells interact with the immune system allowed the
development of immunotherapeutic strategies, harnessing patients' immune system to fight …