Background Airway oedema (swelling) and mucus plugging are the principal pathological
features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (≥ 3%) …

BACKGROUND AND OBJECTIVE: The mainstay of treatment for acute bronchiolitis remains
supportive care. The objective of this study was to assess the efficacy and safety of …

目的评价高渗盐水治疗婴幼儿毛细支气管炎的疗效和安全性, 为临床治疗提供依据.
方法检索PubMed, EMBASE, Cochrane 图书馆, Cochrane 临床对照试验库, 维普中文科技期刊 …

Importance Bronchiolitis is one of the most common and costly respiratory diseases in
infants and young children. Previous studies have shown a potential benefit of nebulized …

Importance Two previous meta-analyses of nebulized hypertonic saline (HS) on hospital
length of stay (LOS) in acute viral bronchiolitis have suggested benefit. Neither study fully …

Importance Acute bronchiolitis is the most frequent lower respiratory tract infection in infants,
yet there are no effective therapies available. Current evidence is unclear about the role of …

BACKGROUND: Monoclonal antibody to respiratory syncytial virus (RSV; palivizumab) is
recommend for prophylaxis of high-risk infants during bronchiolitis seasons but not for RSV …

The pathogenesis of lung disease in cystic fibrosis is characterised by decreased airway
surface liquid volume and subsequent failure of normal mucociliary clearance. Mucus within …

BACKGROUND: Research suggests that hypertonic saline (HS) may improve mucous flow
in infants with acute bronchiolitis. Data suggest a trend favoring reduced length of hospital …

OBJECTIVE: Determine whether dexamethasone treatment added to salbutamol reduces
time to readiness for discharge in patients with bronchiolitis and possible asthma …