Plant-based approaches for rheumatoid arthritis regulation: mechanistic insights on pathogenesis, molecular pathways, and delivery systems

A Bhoi, SD Dwivedi, D Singh… - Critical Reviews™ in …, 2024 - dl.begellhouse.com
Rheumatoid arthritis (RA) is classified as a chronic inflammatory autoimmune disorder,
associated with a varied range of immunological changes, synovial hyperplasia, cartilage …

Explainable artificial intelligence-assisted virtual screening and bioinformatics approaches for effective bioactivity prediction of phenolic cyclooxygenase-2 (COX-2) …

M Rudrapal, KK Kirboga, M Abdalla, S Maji - Molecular Diversity, 2024 - Springer
Abstract Cyclooxygenase-2 (COX-2) inhibitors are nonsteroidal anti-inflammatory drugs that
treat inflammation, pain and fever. This study determined the interaction mechanisms of …

[HTML][HTML] Biological Potential of Aromadendrin Against Human Disorders: Recent Development in Pharmacological Activities and Analytical Aspects

K Patel, DK Patel - Pharmacological Research-Modern Chinese Medicine, 2024 - Elsevier
Introduction Medicinal plants have played an essential role in the treatment of human
diseases and their associated secondary complications since early childhood in the medical …

Discovering the Active Ingredients of Medicine and Food Homologous Substances for Inhibiting the Cyclooxygenase-2 Metabolic Pathway by Machine Learning …

Y Tian, Z Zhang, A Yan - Molecules, 2023 - mdpi.com
Cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase (mPGES-1) are two
key targets in anti-inflammatory therapy. Medicine and food homology (MFH) substances …

Computational study unravels inhibitory potential of epicatechin gallate against inflammatory and pyroptosis‐associated mediators in COVID‐19

P Rajak, A Ganguly - MedComm–Future Medicine, 2023 - Wiley Online Library
Abstract Coronavirus disease‐19 (COVID‐19) is the global health emergency caused by
SARS‐CoV‐2. Upon infection, antigenic determinants of the virus trigger massive production …

Phytochemical investigation on Ginkgo biloba L.(Ginkgoaceae) and its chemotaxonomic significance

MA Zeb, WC Tu, XL Li, WL Xiao - Biochemical Systematics and Ecology, 2024 - Elsevier
A phytochemical study conducted on Ginkgo biloba L. led to the isolation and purification of
sixteen compounds which include one bilobalide (1), one ginkgolide (2), one dipeptide (3) …

Molecular insights on the formation of inclusion complexes between Natural and Synthetic cyclodextrins and 7-O-methyl-aromadendrin

V Irani, AHJ Magham - Journal of Molecular Structure, 2024 - Elsevier
This study examines the use of cyclodextrins (CDs) to improve the stability, bioavailability,
and water solubility of 7-O-methyl-aromadendrin (7-OMA), a natural compound with …