Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Significance: Chronic wounds impact the quality of life (QoL) of nearly 2.5% of the total
population in the United States and the management of wounds has a significant economic …

Mycobacteriophages—bacteriophages infecting Mycobacterium hosts—contribute
substantially to our understanding of viral diversity and evolution, provide resources for …

The canonical lytic–lysogenic binary has been challenged in recent years, as more
evidence has emerged on alternative bacteriophage infection strategies. These infection …

Bacteriophages are enigmatic entities that defy definition. Classically, they are specialist
viruses that exclusively parasitize bacterial hosts. Yet this definition becomes limiting when …

Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …

Bacteriophages, viruses that infect and replicate within bacteria, impact bacterial responses
to antibiotics in complex ways. Recent studies using lytic bacteriophages to treat bacterial …

Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in a variety of
settings. Many P. aeruginosa isolates are infected by filamentous Pf bacteriophage …

Bacteria-infecting viruses (phages) and their hosts maintain an ancient and complex
relationship. Bacterial predation by lytic phages drives an ongoing phage-host arms race …

Adjunctive phage therapy was used in an attempt to avoid catastrophic outcomes from
extensive chronic Pseudomonas aeruginosa osteoarticular infection in a 7‐year‐old child …