[HTML][HTML] Immune responses to human fungal pathogens and therapeutic prospects
MS Lionakis, RA Drummond, TM Hohl - Nature Reviews Immunology, 2023 - nature.com
Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …
From intestinal colonization to systemic infections: Candida albicans translocation and dissemination
Candida species are the most prevalent cause of invasive fungal infections, of which
Candida albicans is the most common. Translocation across the epithelial barrier into the …
Candida albicans is the most common. Translocation across the epithelial barrier into the …
The hyphal-specific toxin candidalysin promotes fungal gut commensalism
The fungus Candida albicans frequently colonizes the human gastrointestinal tract, from
which it can disseminate to cause systemic disease. This polymorphic species can transition …
which it can disseminate to cause systemic disease. This polymorphic species can transition …
Friendly fungi: symbiosis with commensal Candida albicans
Mucosal tissues are constitutively colonized by a wide assortment of host-adapted microbes.
This includes the polymorphic fungus Candida albicans which is a primary target of human …
This includes the polymorphic fungus Candida albicans which is a primary target of human …
[HTML][HTML] Healthy Diet and Lifestyle improve the gut microbiota and help combat fungal infection
S Jawhara - Microorganisms, 2023 - mdpi.com
Western diets are rapidly spreading due to globalization, causing an increase in obesity and
diseases of civilization. These Western diets are associated with changes in the gut …
diseases of civilization. These Western diets are associated with changes in the gut …
[HTML][HTML] The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition of Candida albicans
ID Jacobsen - Current Clinical Microbiology Reports, 2023 - Springer
Abstract Purpose of Review The fungus Candida albicans has evolved to live in close
association with warm-blooded hosts and is found frequently on mucosal surfaces of healthy …
association with warm-blooded hosts and is found frequently on mucosal surfaces of healthy …
[HTML][HTML] IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis
N Millet, NV Solis, D Aguilar, MS Lionakis… - Nature …, 2022 - nature.com
During infection the host relies on pattern-recognition receptors to sense invading fungal
pathogens to launch immune defense mechanisms. While fungal recognition and immune …
pathogens to launch immune defense mechanisms. While fungal recognition and immune …
[HTML][HTML] Intestinal fungi and antifungal secretory immunoglobulin A in Crohn's disease
M Sun, J Ju, H Xu, Y Wang - Frontiers in Immunology, 2023 - frontiersin.org
The human gastrointestinal tract harbors trillions of commensal microorganisms. Emerging
evidence points to a possible link between intestinal fungal dysbiosis and antifungal …
evidence points to a possible link between intestinal fungal dysbiosis and antifungal …
[HTML][HTML] Antibodies as Models and Tools to Decipher Candida albicans Pathogenic Development: Review about a Unique Monoclonal Antibody Reacting with …
J Leroy, K Lecointe, P Coulon, B Sendid, R Robert… - Journal of Fungi, 2023 - mdpi.com
Candidiasis, caused mainly by Candida albicans, a natural commensal of the human
digestive tract and vagina, is the most common opportunistic fungal infection at the mucosal …
digestive tract and vagina, is the most common opportunistic fungal infection at the mucosal …
[HTML][HTML] Microbial underdogs: exploring the significance of low-abundance commensals in host-microbe interactions
G Han, S Vaishnava - Experimental & Molecular Medicine, 2023 - nature.com
Our understanding of host-microbe interactions has broadened through numerous studies
over the past decades. However, most investigations primarily focus on the dominant …
over the past decades. However, most investigations primarily focus on the dominant …