The second European evidenced-based consensus on reproduction and pregnancy in inflammatory bowel disease

CJ Van der Woude, S Ardizzone… - Journal of Crohn's …, 2015 - academic.oup.com
Trying to conceive and being pregnant is an emotional period for those involved. In the
majority of patients suffering from inflammatory bowel disease, maintenance therapy is …

[HTML][HTML] Risk factors for venous and arterial thrombosis

E Previtali, P Bucciarelli, SM Passamonti… - Blood …, 2011 - ncbi.nlm.nih.gov
Thrombophilia is considered as a condition predisposing to the development of thrombosis.
Arterial thrombosis usually occurs after the erosion or rupture of an atherosclerotic plaque …

Oral contraceptives and the risk of venous thrombosis

JP Vandenbroucke, J Rosing… - … England Journal of …, 2001 - Mass Medical Soc
In the early 1960s, shortly after the introduction of oral contraceptives, the first case reports
appeared describing venous thrombosis and pulmonary emboli in women using this method …

Safety concerns and health benefits associated with oral contraception

R Burkman, JJ Schlesselman, M Zieman - American journal of obstetrics …, 2004 - Elsevier
Since the introduction of hormonal contraceptives in the 1960s, there have been a variety of
both health benefits and safety concerns attributed to their use. In most instances, the …

Thrombotic risk factors: basic pathophysiology

I Martinelli, P Bucciarelli, PM Mannucci - Critical care medicine, 2010 - journals.lww.com
Although venous thrombosis has been traditionally associated with stasis and
hypercoagulability, arterial thrombosis is mainly associated with heightened platelet …

Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study

J Rosing, S Middeldorp, J Curvers, MCL GDlig… - The Lancet, 1999 - thelancet.com
Background We have reported previously that, compared with use of second-generation oral
contraceptives, the use of third-generation oral contraceptives is associated with increased …

European evidenced-based consensus on reproduction in inflammatory bowel disease

CJ van der Woude, S Kolacek, I Dotan… - Journal of Crohn's …, 2010 - academic.oup.com
Inflammatory bowel diseases (IBD) typically affect patients in their reproductive years. It has
been shown that reproductive issues are of key concern to IBD patients, 1 especially …

Surrogate end points in clinical research: hazardous to your health

DA Grimes, KF Schulz - Obstetrics & Gynecology, 2005 - journals.lww.com
Surrogate end points in clinical research pose real danger. A surrogate end point is an
outcome measure, commonly a laboratory test, that substitutes for a clinical event of true …

Safety of medical treatments for endometriosis

N Berlanda, E Somigliana, P Viganò… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: All medical treatments for endometriosis are equally effective in relieving pain.
However, all of them alleviate pain symptoms for as long as they are used, but pain always …

Oral contraceptives: current status

RT Burkman - Clinical obstetrics and gynecology, 2001 - journals.lww.com
The turn of this century marked the fourth decade of oral contraceptive use. Although there
has been a wealth of literature that has shown “the pill” to be safe and effective, there …