[HTML][HTML] Bio-scaffolds as cell or exosome carriers for nerve injury repair

R Poongodi, YL Chen, TH Yang, YH Huang… - International journal of …, 2021 - mdpi.com
Central and peripheral nerve injuries can lead to permanent paralysis and organ
dysfunction. In recent years, many cell and exosome implantation techniques have been …

Cell-seeded biomaterial scaffolds: the urgent need for unanswered accelerated angiogenesis

H Shokrani, A Shokrani, SM Sajadi, F Seidi… - International journal …, 2022 - Taylor & Francis
One of the most arduous challenges in tissue engineering is neovascularization, without
which there is a lack of nutrients delivered to a target tissue. Angiogenesis should be …

Hyaluronan-based hydrogel integrating exosomes for traumatic brain injury repair by promoting angiogenesis and neurogenesis

X Liu, C Wu, Y Zhang, S Chen, J Ding, Z Chen… - Carbohydrate …, 2023 - Elsevier
With wide clinical demands, therapies for traumatic brain injury (TBI) are far from satisfactory.
Combining the merits of stem cells but avoiding the risk of immunologic rejection, bone …

Integrated printed BDNF-stimulated HUCMSCs-derived exosomes/collagen/chitosan biological scaffolds with 3D printing technology promoted the remodelling of …

X Liu, J Zhang, X Cheng, P Liu, Q Feng… - Regenerative …, 2023 - academic.oup.com
The restoration of nerve dysfunction after traumatic brain injury (TBI) faces huge challenges
due to the limited self-regenerative abilities of nerve tissues. In situ inductive recovery can …

Electrospun piezoelectric scaffold with external mechanical stimulation for promoting regeneration of peripheral nerve injury

H Zhang, D Lan, B Wu, X Chen, X Li, Z Li… - …, 2023 - ACS Publications
Safe and efficient provision of electrical stimulation (ES) for nerve repair and regeneration is
a problem that needs to be addressed. In this study, a silk fibroin/poly (vinylidene fluoride-co …

Dual-enzymatically cross-linked gelatin hydrogel promotes neural differentiation and neurotrophin secretion of bone marrow-derived mesenchymal stem cells for …

J Li, D Zhang, S Guo, C Zhao, L Wang, S Ma… - International Journal of …, 2021 - Elsevier
Traumatic brain injury (TBI) is one of the most devastating nervous injuries. Neural tissue
engineering based on stem cells and bioactive scaffold is a promising but challenging …

[HTML][HTML] Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance …

XY Liu, YH Feng, QB Feng, JY Zhang… - Neural Regeneration …, 2023 - journals.lww.com
There are various clinical treatments for traumatic brain injury, including surgery, drug
therapy, and rehabilitation therapy; however, the therapeutic effects are limited. Scaffolds …

Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β‐catenin signaling pathway

D Zhu, Z Wang, G Zhang, C Ma, X Qiu… - The FASEB …, 2022 - Wiley Online Library
Intervertebral disc (IVD) degeneration (IVDD) is closely linked to degenerative spinal
disease, resulting in disability, poor quality of life, and financial burden. Apoptosis of nucleus …

[HTML][HTML] The application of collagen in the repair of peripheral nerve defect

X Li, X Zhang, M Hao, D Wang, Z Jiang… - … in Bioengineering and …, 2022 - frontiersin.org
Collagen is a natural polymer expressed in the extracellular matrix of the peripheral nervous
system. It has become increasingly crucial in peripheral nerve reconstruction as it was …

[HTML][HTML] 3D printing of injury-preconditioned secretome/collagen/heparan sulfate scaffolds for neurological recovery after traumatic brain injury in rats

XY Liu, ZH Chang, C Chen, J Liang, JX Shi… - Stem Cell Research & …, 2022 - Springer
Background The effects of traumatic brain injury (TBI) can include physical disability and
even death. The development of effective therapies to promote neurological recovery is still …