Abstract Kruppel‐like factor 14 (KLF14) is a newly identified member of the KLF family.
Expression of KLF14 is induced by TGF‐β in intrauterine and ectodermal tissue. Initial …

The Krüppel-like factor (KLF) family, as the SP/XKLF transcription factors, plays important
roles in regulating the expression of genes required for the proper execution of important …

Rapamycin treatment has positive and negative effects on progression of type 2 diabetes
(T2D) in a recombinant inbred polygenic mouse model, male NONcNZO10/LtJ (NcZ10) …

Background Metastasis is one of the most lethal hallmarks of esophageal squamous cell
carcinoma (ESCC), yet the mechanisms remain unclear due to a lack of reliable …

To examine the effects of piperine on lipid metabolism in white adipose tissue of high-fat diet
induced obese mice, mice were divided into CON, HFD, HFD+ Pip15, and HFD+ Pip30 …

Abstract Study Objective: Increased visceral white adipose tissue (vWAT) mass results in
infiltration of inflammatory macrophages that drive inflammation and insulin resistance …

Type 2 diabetes is an age-and-obesity associated disease driven by impairments in glucose
homeostasis that ultimately result in defective insulin secretion from pancreatic β-cells. To …

Mesoderm specific transcript (Mest)/paternally expressed gene-1 (Peg1) is an imprinted
gene expressed predominantly from the paternal allele. Aberrations in maternal behavior …

Background and aims Krüppel-like factor 14 (KLF14) is known to play a role in
atherosclerosis, but the underlying mechanisms are still largely unknown. The aim of our …

Interindividual variation of white adipose tissue (WAT) expression of mesoderm specific
transcript (Mest), a paternally-expressed imprinted gene belonging to the α/β-hydrolase fold …