Chronic liver disease mediated by activation of hepatic stellate cells (HSCs) and Kupffer
cells (KCs) leads to liver fibrosis. Here, we aimed to investigate the molecular mechanism …

Prostate cancer continues to be the most common nonskin cancer diagnosed and the
second leading cause of cancer death in men in the United States. Prostate cancer that has …

The hepatoprotective effects of purple sweet potato color (PSPC), which is natural
anthocyanin food colors, have been well demonstrated in many studies. Nevertheless, little …

Chemokines are a class of small chemotactic molecules with cytokine-like functions, which
are well known to orchestrate inflammatory responses within different organs. Overall, more …

Despite increasing knowledge about molecular pathways in pathogenesis of chronic liver
disease, selective therapeutic options are scarce, especially in advanced diseases …

Noninfectious liver injury causes many acute and chronic liver diseases around the globe,
and particularly in developed nations. Bone marrow‐derived monocytes infiltrate the …

Objectives To seek evidence for the role of hypoxia in early human tendinopathy, and
thereafter to explore mechanisms whereby tissue hypoxia may regulate apoptosis …

Background & Aims CC motif chemokine receptor 2 (CCR2) has been recognized as a
promising target for the treatment of liver fibrosis. PC3-secreted microprotein (PSMP) …

BACKGROUND & AIMS: Liver fibrogenesis is sustained by myofibroblast-like cells
originating from hepatic stellate cells (HSC/MFs), portal fibroblasts or bone marrow-derived …

Liver cirrhosis is a major cause of morbidity and mortality worldwide and has very limited
therapeutic options. Regardless of the aetiology, hepatic fibrosis is a characteristic feature of …