Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis

K Rombouts, F Marra - Digestive diseases, 2010 - karger.com
Non-alcoholic fatty liver disease (NAFLD) has become the most common liver disease in
Western countries. The more severe form of this condition, non-alcoholic steatohepatitis …

A polysaccharide from Dendrobium huoshanense prevents hepatic inflammatory response caused by carbon tetrachloride

CC Tian, XQ Zha, JP Luo - Biotechnology & Biotechnological …, 2015 - Taylor & Francis
Dendrobium huoshanense is a precious herbal medicine in China, which exhibits a variety
of restorative and therapeutic effects. This study aimed at investigating the hepatoprotective …

Lactobacillus rhamnosus GG Ameliorates Liver Injury and Hypoxic Hepatitis in Rat Model of CLP-Induced Sepsis

L Ding, Y Gong, Z Yang, B Zou, X Liu, B Zhang… - Digestive diseases and …, 2019 - Springer
Background Probiotic use to prevent gastrointestinal infections in critical care has shown
great promise in recent clinical trials. Although well-documented benefits of probiotic use in …

Adipokines and redox signaling: impact on fatty liver disease

M Parola, F Marra - Antioxidants & Redox Signaling, 2011 - liebertpub.com
Adipokines (adipose tissue cytokines) are polypeptide factors secreted by adipose tissue in
a highly regulated manner. The 'classical'adipokines (leptin, adiponectin, and resistin) are …

Protective effects of theasinensin A against carbon tetrachloride-induced liver injury in mice

WL Hung, G Yang, YC Wang, YS Chiou, YC Tung… - Food & function, 2017 - pubs.rsc.org
Theasinensins have been identified as a major group of unique catechin dimers mainly
found in oolong tea and black tea. Among several types of theasinensins, theasinensin A …

Protective effect of selenium‐enriched red radish sprouts on carbon tetrachloride‐induced liver injury in mice

L Jia, T Wang, Y Sun, M Zhang, J Tian… - Journal of food …, 2019 - Wiley Online Library
This study aimed to investigate the effect of Se (Selenium) treatment on nutritional quality in
radish sprouts. The results showed that 15 µM sodium selenite significantly increased …

[HTML][HTML] Deficiency for the chemokine monocyte chemoattractant protein-1 aggravates tubular damage after renal ischemia/reperfusion injury

I Stroo, N Claessen, GJD Teske, LM Butter, S Florquin… - PloS one, 2015 - journals.plos.org
Temporal expression of chemokines is a crucial factor in the regulation of renal
ischemia/reperfusion (I/R) injury and repair. Beside their role in the migration and activation …

[HTML][HTML] Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine–choline-deficient diet

KM Kassel, GL Guo, O Tawfik, JP Luyendyk - Laboratory investigation, 2010 - Elsevier
Abstract Monocyte chemoattractant protein-1 (MCP-1, Ccl2) expression is increased in livers
of patients with nonalcoholic steatohepatitis and in murine models of steatohepatitis. Several …

Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury

K Zahedi, SL Barone, J Xu… - American Journal …, 2012 - journals.physiology.org
Activation of spermine/spermidine-N 1-acetyltransferase (SSAT) leads to DNA damage and
growth arrest in mammalian cells, and its ablation reduces the severity of ischemic and …

Editor's Highlight: Farnesoid X receptor protects against low-dose carbon tetrachloride-induced liver injury through the taurocholate-JNK pathway

S Takahashi, N Tanaka, S Golla, T Fukami… - Toxicological …, 2017 - academic.oup.com
Hepatotoxicity is of major concern for humans exposed to industrial chemicals and drugs.
Disruption of farnesoid X receptor (FXR), a master regulator of bile acid (BA) metabolism …