Cisplatin continues to play a central role in cancer chemotherapy in spite of its toxicity. It is
used as first-line chemotherapy against epithelial malignancies of lung, ovarian, bladder …

Drugs are discovered through the biological screening of collections of compounds,
followed by optimization toward functional end points. The properties of screening …

Chemotherapeutic agents are part of the standard treatment algorithms for many
malignancies; however, their application and dosage are limited by their toxic effects to …

Blocking cell division through the inhibition of mitosis is one of the most successful clinical
strategies for the treatment of cancer. Taxanes and vinca alkaloids are in widespread use …

Colorectal cancers commonly carry truncation mutations in the adenomatous polyposis coli
(APC) gene. The APC protein contributes to the stabilization of microtubules. Consistently …

Pancreatic cancer (PC) is a lethal disease which is characterized by chemoresistance.
Components of the cell cytoskeleton are therapeutic targets in cancer. βIV-tubulin is one …

Drugs derived from natural products, particularly from plants, are the leads of clinically used
anticancer agents. Plant-derived anticancer agents in clinical use consist of the Vinca …

Recognize and treat fatigue as a major symptom of cancer and cancer treatment! The
Handbook of Cancer-Related Fatigue, by Dr. Roberto Patarca-Montero, the editor of the …

A handy reference guide to living with fatigue! Medical Etiology, Assessment, and Treatment
of Chronic Fatigue and Malaise: Clinical Differentiation and Intervention is the single …

В нашей стране злокачественные опухоли желудочно кишечного трак та (ЖКТ)
составляют в структуре заболеваемости у мужчин 30, 5% и у женщин 26, 1%, а в …