[HTML][HTML] Targeting ferroptosis: New perspectives of Chinese herbal medicine in the treatment of diabetes and its complications
C Liu, W Wang, J Gu - Heliyon, 2023 - cell.com
Ferroptosis is a non-apoptotic mode of cell death. A large number of studies have confirmed
that ferroptosis plays a vital role in the occurrence and development of diabetes and diabetic …
that ferroptosis plays a vital role in the occurrence and development of diabetes and diabetic …
[HTML][HTML] Copper metabolism and its role in diabetic complications: A review
D Jia, L Liu, W Liu, J Li, X Jiang, Y Xin - Pharmacological Research, 2024 - Elsevier
Disturbances in copper (Cu) homeostasis have been observed in diabetes and associated
complications. Cu is an essential micronutrient that plays important roles in various …
complications. Cu is an essential micronutrient that plays important roles in various …
[HTML][HTML] Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7
M Gong, Y Guo, H Dong, W Wu, F Wu, F Lu - Biomedicine & …, 2023 - Elsevier
Objectives Diabetic kidney disease (DKD) is a prevalent microvascular complication of
diabetes. Inhibiting the epithelial-mesenchymal transition (EMT) of proximal tubule epithelial …
diabetes. Inhibiting the epithelial-mesenchymal transition (EMT) of proximal tubule epithelial …
[HTML][HTML] Modified Hu-lu-ba-wan protects diabetic glomerular podocytes via promoting PKM2-mediated mitochondrial dynamic homeostasis
M Gong, Y Guo, H Dong, F Wu, Q He, J Gong, F Lu - Phytomedicine, 2024 - Elsevier
Background Mitochondrial dysfunction is implicated in the progression of diabetic kidney
disease (DKD). Damaged mitochondria produce excessive reactive oxygen species (ROS) …
disease (DKD). Damaged mitochondria produce excessive reactive oxygen species (ROS) …
METTL14 promotes the development of diabetic kidney disease by regulating m6A modification of TUG1
Y Zheng, Z Zhang, D Zheng, P Yi, S Wang - Acta Diabetologica, 2023 - Springer
Background Diabetic kidney disease (DKD) is one of the most common diabetic
complications. Endoplasmic reticulum stress (ERS) is an important step for renal tubular …
complications. Endoplasmic reticulum stress (ERS) is an important step for renal tubular …
[HTML][HTML] Phenylsulfate-induced oxidative stress and mitochondrial dysfunction in podocytes are ameliorated by Astragaloside IV activation of the SIRT1/PGC1α/Nrf1 …
L Li, J Zou, M Zhou, H Li, T Zhou, X Liu, Q Huang… - Biomedicine & …, 2024 - Elsevier
Abstract Astragaloside IV (AS-IV) exhibits diverse biological activities. Despite this, the
detailed molecular mechanisms by which AS-IV ameliorates diabetic nephropathy (DN) and …
detailed molecular mechanisms by which AS-IV ameliorates diabetic nephropathy (DN) and …
Iridoids modulate inflammation in diabetic kidney disease: A review
T Zhou, N Tian, L Li, R Yu - Journal of Integrative Medicine, 2024 - Elsevier
In recent years, preclinical research on diabetic kidney disease (DKD) has surged to the
forefront of scientific and clinical attention. DKD has become a pervasive complication of …
forefront of scientific and clinical attention. DKD has become a pervasive complication of …
LRG1 contributes to the pathogenesis of multiple kidney diseases: a comprehensive review
C Chen, J Zhang, T Yu, H Feng, J Liao, Y Jia - Kidney Dis (Basel), 2024 - karger.com
Background: The increasing prevalence of kidney diseases has become a significant public
health issue, with a global prevalence exceeding 10%. In order to accurately identify …
health issue, with a global prevalence exceeding 10%. In order to accurately identify …
[HTML][HTML] Uncovering the mechanism of Qidan Dihuang Granule in the treatment of diabetic kidney disease combined network pharmacology, UHPLC-MS/MS with …
L Xiang, X Cai, X Zhao, Y Liu, Y Xiao, P Jiang, L Yin… - Heliyon, 2023 - cell.com
Abstract Background and aim Diabetic Kidney Disease (DKD) is a common microvascular
complication of diabetes mellitus. Multi-center, randomized controlled trials have shown that …
complication of diabetes mellitus. Multi-center, randomized controlled trials have shown that …
[HTML][HTML] Nicotinamide protects against diabetic kidney disease through regulation of Sirt1
Y Yang, J Huang, L Xie, Y Wang, S Guo, M Wang… - Endocrine, 2024 - Springer
Purpose To investigate the effect of nicotinamide (Nam) on diabetic kidney disease (DKD) in
mice and explore its mechanism. Methods Thirty DBA/2 J mice were randomly assigned to …
mice and explore its mechanism. Methods Thirty DBA/2 J mice were randomly assigned to …