Since the discovery of osteoinduction in the early 20th century, innovative biomaterials with
osteoinductive potential have emerged. Over the last 50 years, however, our ability to …

A literature review was performed to survey the available information on the potential of
bone growth factors in skeletal reconstruction in the maxillofacial area. The aim of this …

Purpose: This study compared two methods of preparing platelet-rich plasma (PRP) gel and
the levels of PDGF and TGFβ in each preparation. Materials and Methods: Platelet-rich …

Background: Growth factors are generally accepted to be essential mediators of tissue repair
via well‐established mechanisms of action that include stimulatory effects on angiogenesis …

The abilities of bone to remodel, fractures to repair, and bone grafts to incorporate are all
fundamental reflections of the bone remodeling cycle. This process is characterized by the …

Objective The focus of this review is to summarize recent advances on regenerative
technologies (scaffolding matrices, cell/gene therapy and biologic drug delivery) to promote …

A bstract The goal of periodontal therapy is to protect and maintain the patient's natural
dentition for his or her lifetime. More specifically, after periodontal regenerative surgery, the …

Platelets have been implicated in accelerated bone regeneration in grafting applications.
The beneficial effects of platelets may involve their ability to stimulate the proliferation of …

The potential of growth factors to stimulate tissue healing through the enhancement of cell
proliferation, migration, and differentiation is undeniable. However, critical parameters on …

The osteogenic factors bone morphogenetic protein (BMP-7), platelet-derived growth factor
(PDGF)-BB, and fibroblast growth factor (FGF-2) regulate the recruitment of osteoprogenitor …