[HTML][HTML] SARS-CoV-2 and the DNA damage response

RJ Grand - Journal of General Virology, 2023 - microbiologyresearch.org
The recent coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is characterized by …

Multiple E3 ligases act as antiviral factors against SARS-CoV-2 via inducing the ubiquitination and degradation of ORF9b

M Yu, J Li, W Gao, Z Li, W Zhang - Journal of Virology, 2024 - Am Soc Microbiol
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) open reading frame 9b
(ORF9b) antagonizes the antiviral type I and III interferon (IFN) responses and is …

[HTML][HTML] Antiviral responses versus virus-induced cellular shutoff: a game of thrones between influenza A virus NS1 and SARS-CoV-2 Nsp1

AM Khalil, A Nogales, L Martínez-Sobrido… - Frontiers in Cellular …, 2024 - ncbi.nlm.nih.gov
Following virus recognition of host cell receptors and viral particle/genome internalization,
viruses replicate in the host via hijacking essential host cell machinery components to evade …

Diversity for endoribonuclease nsp15-mediated regulation of alpha-coronavirus propagation and virulence

Y Xie, C Chen, D Zhang, Z Jiao, Y Chen… - Microbiology …, 2023 - Am Soc Microbiol
Endoribonuclease non-structural protein 15 (nsp15)(EndoU) is conserved among
coronaviruses (CoVs) and is crucial for viral replication, evasion of the innate immune …

Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10

BD Lopez-Ayllon, S Marin, M Farinas Fernandez… - bioRxiv, 2023 - biorxiv.org
Antiviral signaling, immune response and cell metabolism in human body are dysregulated
by SARS-CoV-2, the causative agent of the COVID-19. Here, we show that SARS-CoV-2 …

Príprava a charakterizácia koronavirusovej exonukleázy nsp14

M Vaško - 2023 - dspace.cuni.cz
Koronaviry jsou obalené viry s genomem tvořeným jednovláknovou molekulou RNA v
pozitivní formě. S velikostí genomu, u některých druhů, přesahující 30 kb představují největší …