The neocortex is densely innervated by basal forebrain (BF) cholinergic neurons. Long-
range axons of cholinergic neurons regulate higher-order cognitive function and dysfunction …

Acetlylcholine (ACh) in the central nervous system is critical for a multitude of functions.
Here, we concentrate on declarative memory in humans, and its equivalent episodic-like …

Striatal cholinergic interneurons (ChIs) are central for the processing and reinforcement of
reward‐related behaviors that are negatively affected in states of altered dopamine …

Introduction: Both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are
present in the body in large amounts. AChE is an important part of the cholinergic nervous …

Neurodegenerative diseases are a large group of neurological disorders with diverse
etiological and pathological phenomena. However, current therapeutics rely mostly on …

The cholinergic systems play a pivotal role in learning and memory, and have been the
centre of attention when it comes to diseases containing cognitive deficits. It is therefore not …

The release of dopamine from terminals in the NAc is regulated by a number of factors,
including voltage-gated ion channels, D2-autoreceptors, and nAChRs. Cholinergic …

Acetylcholine (ACh) signaling shapes neuronal circuit development and underlies specific
aspects of cognitive functions and behaviors, including attention, learning, memory and …

The nicotinic system plays an important role in ordinary cognition, particularly in attention.
The main nicotinic receptor in the human brain is the heteromeric α4β2 neuronal nicotinic …

Abstract Background Ganoderma (Lingzhi in Chinese) has shown good clinical outcomes in
the treatment of insomnia, restlessness, and palpitation. However, the mechanism by which …