Current applications of polycaprolactone as a scaffold material for heart regeneration

PR Schmitt, KD Dwyer… - ACS Applied Bio Materials, 2022 - ACS Publications
Despite numerous advances in treatments for cardiovascular disease, heart failure (HF)
remains the leading cause of death worldwide. A significant factor contributing to the …

Diabetic cardiomyopathy: recent evidence from mouse models of type 1 and type 2 diabetes

DL Severson - Canadian journal of physiology and …, 2004 - cdnsciencepub.com
La cardiomyopathie diabétique est définie comme une dysfonction ventriculaire du c ur du
diabétique en l'absence de coronaropathie. À l'aide de techniques in vivo et ex vivo …

GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice

MH Noyan-Ashraf, MA Momen, K Ban, AM Sadi… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Glucagon-like peptide-1 receptor (GLP-1R) agonists are used to treat type 2
diabetes, and transient GLP-1 administration improved cardiac function in humans after …

Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice

MD Majmudar, EJ Keliher, T Heidt, F Leuschner… - Circulation, 2013 - Am Heart Assoc
Background—Exaggerated and prolonged inflammation after myocardial infarction (MI)
accelerates left ventricular remodeling. Inflammatory pathways may present a therapeutic …

Echocardiography in mice

S Gao, D Ho, DE Vatner… - Current protocols in mouse …, 2011 - Wiley Online Library
Murine models have been utilized with increasing frequency mainly due to availability of
genetically engineered models. With advancement in high spatial and temporal resolution …

PET/MRI of inflammation in myocardial infarction

WW Lee, B Marinelli, AM Van Der Laan… - Journal of the American …, 2012 - jacc.org
Objectives: The aim of this study was to explore post–myocardial infarction (MI) myocardial
inflammation. Background: Innate immune cells are centrally involved in infarct healing and …

Impaired Infarct Healing in Atherosclerotic Mice With Ly-6ChiMonocytosis

P Panizzi, FK Swirski, JL Figueiredo… - Journal of the American …, 2010 - jacc.org
Objectives: The aim of this study was to test whether blood monocytosis in mice with
atherosclerosis affects infarct healing. Background: Monocytes are cellular protagonists of …

Echocardiographic speckle-tracking based strain imaging for rapid cardiovascular phenotyping in mice

M Bauer, S Cheng, M Jain, S Ngoy… - Circulation …, 2011 - Am Heart Assoc
Rationale: High-sensitivity in vivo phenotyping of cardiac function is essential for evaluating
genes of interest and novel therapies in small animal models of cardiovascular disease …

[HTML][HTML] Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice

A Diwan, M Krenz, FM Syed… - The Journal of …, 2007 - Am Soc Clin Investig
Following myocardial infarction, nonischemic myocyte death results in infarct expansion,
myocardial loss, and ventricular dysfunction. Here, we demonstrate that a specific …

Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto‐optical nanoparticle

DE Sosnovik, EA Schellenberger… - … in Medicine: An …, 2005 - Wiley Online Library
The ability to image cardiomyocyte apoptosis in vivo with high‐resolution MRI could facilitate
the development of novel cardioprotective therapies. The sensitivity of the novel …