Abstract Missale, Cristina, S. Russel Nash, Susan W. Robinson, Mohamed Jaber, and Marc
G. Caron. Dopamine Receptors: From Structure to Function. Physiol. Rev. 78: 189–225 …

This review updates the existing knowledge suggesting a role for the D3 receptor in
schizophrenia and drug addiction. The D3 receptor is expressed in brain regions controlling …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

In the central nervous system (CNS), dopamine is involved in the control of locomotion,
cognition, affect and neuroendocrine secretion. These actions of dopamine are mediated by …

The description of new dopamine (DA) receptor subtypes, D1-(D1 and D5) and D2-like
(D2A, D2B, D3, D4), has given an impetus to DA research. While selective agonists and …

Locomotor activity is a polygenic trait that varies widely among inbred strains of mice. To
characterize the role of D2 dopamine receptors in locomotion, we generated F2hybrid …

In treating Parkinson's disease with dopaminergic agonists, such as pramipexole, ropinirole,
pergolide, rotigotine, apomorphine, or bromocriptine, it has been observed that a significant …

Dopamine is a major neurotransmitter in the central nervous system. Receptors for this
catecholamine are of considerable interest, as they are the principal target of drugs …

The D 2 and D 3 receptors (D 2 R and D 3 R), which are potential targets for antipsychotic
drugs, have a similar structural architecture and signaling pathway. Furthermore, in some …

Neurobiology of retinal dopamine is reviewed and discussed in relation to degenerative
states of the tissue. The Introduction deals with the basic physiological actions of dopamine …