Non-antibiotic compounds associated with humans and the environment can promote horizontal transfer of antimicrobial resistance genes

I Alav, MMC Buckner - Critical Reviews in Microbiology, 2023 - Taylor & Francis
Horizontal gene transfer plays a key role in the global dissemination of antimicrobial
resistance (AMR). AMR genes are often carried on self-transmissible plasmids, which are …

[HTML][HTML] Cobalt complexes modulate plasmid conjugation in Escherichia coli and Klebsiella pneumoniae

I Alav, P Pordelkhaki, PE de Resende, H Partington… - Scientific Reports, 2024 - nature.com
Antimicrobial resistance genes (ARG), such as extended-spectrum β-lactamase (ESBL) and
carbapenemase genes, are commonly carried on plasmids. Plasmids can transmit between …

Inorganic Polyphosphate Affects Biofilm Assembly, Capsule Formation, and Virulence of Hypervirulent ST23 Klebsiella pneumoniae

D Rojas, AE Marcoleta, M Gálvez-Silva… - ACS Infectious …, 2024 - ACS Publications
The emergence of hypervirulent Klebsiella pneumoniae (hvKP) strains poses a significant
threat to public health due to high mortality rates and propensity to cause severe community …

Chitosan oligosaccharide accelerates the dissemination of antibiotic resistance genes through promoting conjugative plasmid transfer

Y Zhang, W Li, Y Wu, X Tian, G Li, Y Zhou, J Sun… - Journal of Hazardous …, 2024 - Elsevier
The dissemination of antibiotic resistance genes (ARGs), especially via plasmid-mediated
horizontal gene transfer, poses a pervasive threat to global health. Chitosan …

Natural products from food sources can alter the spread of AMR plasmids in Enterobacterales

I Alav, P Pordelkhaki, J Rodriguez Navarro, O Neo… - bioRxiv, 2024 - biorxiv.org
Antimicrobial resistance (AMR) poses a significant threat to global public health. Notably,
resistance to carbapenem and extended-spectrum beta-lactam antibiotics in Gram-negative …