Aquaporin water channels in the nervous system
MC Papadopoulos, AS Verkman - Nature Reviews Neuroscience, 2013 - nature.com
The aquaporins (AQPs) are plasma membrane water-transporting proteins. AQP4 is the
principal member of this protein family in the CNS, where it is expressed in astrocytes and is …
principal member of this protein family in the CNS, where it is expressed in astrocytes and is …
[HTML][HTML] Physiology of cholangiocytes
JH Tabibian, AI Masyuk, TV Masyuk… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
Cholangiocytes are epithelial cells that line the intra-and extrahepatic ducts of the biliary
tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived …
tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived …
Human aquaporins: functional diversity and potential roles in infectious and non-infectious diseases
Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …
The aquaporin-4 water channel as a potential drug target in neurological disorders
AS Verkman, AJ Smith, P Phuan… - Expert opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Aquaporin-4 (AQP4) is a water transporting protein expressed at
the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis …
the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis …
Diversity and evolution of membrane intrinsic proteins
Abstract Background Membrane intrinsic proteins (MIPs) are the proteins in charge of
regulating water transport into cells. Because of this essential function, the MIP family is …
regulating water transport into cells. Because of this essential function, the MIP family is …
Human aquaporin-5 facilitates hydrogen peroxide permeation affecting adaption to oxidative stress and cancer cell migration
C Rodrigues, C Pimpão, AF Mósca, AS Coxixo… - Cancers, 2019 - mdpi.com
Reactive oxygen species (ROS), including H2O2, contribute to oxidative stress and may
cause cancer initiation and progression. However, at low concentrations, H2O2 can regulate …
cause cancer initiation and progression. However, at low concentrations, H2O2 can regulate …
Chemokine-dependent T cell migration requires aquaporin-3–mediated hydrogen peroxide uptake
M Hara-Chikuma, S Chikuma, Y Sugiyama… - Journal of Experimental …, 2012 - rupress.org
Chemokine-dependent trafficking is indispensable for the effector function of antigen-
experienced T cells during immune responses. In this study, we report that the water/glycerol …
experienced T cells during immune responses. In this study, we report that the water/glycerol …
Disorders of erythrocyte hydration
PG Gallagher - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
The erythrocyte contains a network of pathways that regulate salt and water content in the
face of extracellular and intracellular osmotic perturbations. This allows the erythrocyte to …
face of extracellular and intracellular osmotic perturbations. This allows the erythrocyte to …
Highlighting membrane protein structure and function: A celebration of the Protein Data Bank
Biological membranes define the boundaries of cells and compartmentalize the chemical
and physical processes required for life. Many biological processes are carried out by …
and physical processes required for life. Many biological processes are carried out by …
Water channel proteins in the gastrointestinal tract
U Laforenza - Molecular aspects of medicine, 2012 - Elsevier
Water transport through the human digestive system is physiologically crucial for
maintaining body water homeostasis and ensure digestive and absorptive functions. Within …
maintaining body water homeostasis and ensure digestive and absorptive functions. Within …