The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …

The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

Renin angiotensin system (RAS) is an endocrine system widely known for its physiological
roles in electrolyte homeostasis, body fluid volume regulation and cardiovascular control in …

Abstract Purpose of Review The renin-angiotensin system (RAS) plays an important role in
modulating cardiovascular function and fluid homeostasis. While the systemic actions of the …

Background Fibroblast growth factor 21 (FGF21) is expressed in several metabolically active
tissues, including liver, fat, and acinar pancreas, and has pleiotropic effects on metabolic …

The regulation of plasma glucose levels is a complex and multifactorial process involving a
network of receptors and signaling pathways across numerous organs that act in concert to …

The alarming rise of cognitive impairment and memory decline and limited effective
solutions present a worldwide concern for dementia patients. The multivariant role of the …

The renin-angiotensin system (RAS), originally described as a circulating hormone system,
is an enzymatic cascade in which the final vasoactive peptide angiotensin II (ANG) regulates …

The brain renin-angiotensin system (RAS) is implicated in control of blood pressure (BP),
fluid intake, and energy expenditure (EE). Angiotensin II (ANG II) within the arcuate nucleus …

The brain renin-angiotensin system plays important roles in blood pressure and
cardiovascular regulation. There are two isoforms of prorenin in the brain: the classic …