Mesenchymal stem cell therapy for ALI/ARDS: Therapeutic potential and challenges

Z Wang, T Yu, Y Hou, W Zhou, Y Ding… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a serious clinical
common disease caused by various pathological factors and can induce serious …

Mesenchymal stromal/stem cells know best: The remarkable complexities of its interactions with polymorphonuclear neutrophils

LT Wang, W Lee, KJ Liu, HK Sytwu, ML Yen… - Stem Cells, 2024 - academic.oup.com
Polymorphonuclear neutrophils (PMNs), the predominant immune cell type in humans, have
long been known as first-line effector cells against bacterial infections mainly through …

Tafazzin deficiency in mouse mesenchymal stem cells promote reprogramming of activated B lymphocytes toward immunosuppressive phenotypes

HM Zegallai, E Abu‐El‐Rub… - The FASEB …, 2022 - Wiley Online Library
Barth Syndrome (BTHS) is a rare X‐linked genetic disorder caused by mutation in the
TAFAZZIN gene. Tafazzin (Taz) deficiency in BTHS patients results in an increased risk of …

[HTML][HTML] Non-canonical functions of myeloperoxidase in immune regulation, tissue inflammation and cancer

JS Lockhart, R Sumagin - International journal of molecular sciences, 2022 - mdpi.com
Myeloperoxidase (MPO) is one of the most abundantly expressed proteins in neutrophils. It
serves as a critical component of the antimicrobial defense system, facilitating microbial …

Rethinking neutrophil extracellular traps

Y Liu, Y Ma, J Yang, J Man, H Wang, Y Li… - International …, 2023 - Elsevier
Neutrophils are a major subset of leukocytes in human circulating blood. In some
circumstances, neutrophils release neutrophil extracellular traps (NETs). lnitially, NETs were …

Stem cell therapies: a new era in the treatment of multiple sclerosis

L Wu, J Lu, T Lan, D Zhang, H Xu, Z Kang… - Frontiers in …, 2024 - frontiersin.org
Multiple Sclerosis (MS) is an immune-mediated condition that persistently harms the central
nervous system. While existing treatments can slow its course, a cure remains elusive. Stem …

[HTML][HTML] Equine muscle derived mesenchymal stem cells loaded with water-soluble curcumin: modulation of neutrophil activation and enhanced protection against …

T Franck, J Ceusters, H Graide, A Niesten… - International Journal of …, 2023 - mdpi.com
We investigated the antioxidant potential of equine mesenchymal stem cells derived from
muscle microbiopsies (mdMSCs), loaded by a water-soluble curcumin lysinate incorporated …

[HTML][HTML] Neutrophil extracellular traps and active myeloperoxidase concentrate in lamellar tissue of equids with naturally occurring laminitis

N Storms, G de la Rebière, T Franck… - Veterinary Immunology …, 2024 - Elsevier
Laminitis is a pathology of the equine digit ultimately leading to a failure of the dermo-
epidermal interface. Neutrophil activation is recognized as a major factor in SIRS-associated …

间充质干细胞促进肌肉组织修复的应用前景

黄勇彬, 王涛, 娄园一, 庞景群, 陈光华 - 中国组织工程研究, 2024 - cjter.com
间充质干细胞促进肌肉组织修复的应用前景 Page 1 Chinese Journal of Tissue Engineering
Research|Vol 28|No.1|January 2024|107 中国组织工程研究 Chinese Journal of Tissue …

Culture and Immunomodulation of Equine Muscle-Derived Mesenchymal Stromal Cells: A Comparative Study of Innovative 2D versus 3D Models Using Equine …

J Duysens, H Graide, A Niesten, A Mouithys-Mickalad… - Cells, 2024 - mdpi.com
Muscle-derived mesenchymal stromal cells (mdMSCs) hold great promise in regenerative
medicine due to their immunomodulatory properties, multipotent differentiation capacity and …