Hairy root culture for mass-production of high-value secondary metabolites

S Srivastava, AK Srivastava - Critical reviews in biotechnology, 2007 - Taylor & Francis
Plant cell cultivations are being considered as an alternative to agricultural processes for
producing valuable phytochemicals. Since many of these products (secondary metabolites) …

Secondary metabolism of hairy root cultures in bioreactors

Y Kim, BE Wyslouzil, PJ Weathers - In Vitro Cellular & Developmental …, 2002 - Springer
In vitro cultures are being considered as an alternative to agricultural processes for
producing valuable secondary metabolites. Most efforts that use differentiated cultures …

Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites

HN Murthy, KS Joseph, KY Paek… - Critical Reviews in …, 2023 - Taylor & Francis
In vitro plant cell and organ cultures are appealing alternatives to traditional methods of
producing valuable specialized metabolites for use as: pharmaceuticals, food additives …

[图书][B] Metabolic engineering of plant secondary metabolism

R Verpoorte, AW Alfermann - 2000 - books.google.com
Plant secondary metabolism is an economically important source of fine chemicals, such as
drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such …

Bioprocessing of differentiated plant in vitro systems

J Steingroewer, T Bley, V Georgiev… - Engineering in Life …, 2013 - Wiley Online Library
Plant cells contain a wide range of interesting secondary metabolites, which are used as
natural pigments and flavoring agents in foods and cosmetics as well as phyto …

Tools for biotechnological production of useful phytochemicals from adventitious root cultures

HN Murthy, VS Dandin, KY Paek - Phytochemistry reviews, 2016 - Springer
Adventitious roots are natural roots which develop from the differentiated cells of any organ
such as leaf, root or stem. These roots are attractive source of phytochemicals due to their …

Mass production of Ajmalicine by bioreactor cultivation of hairy roots of Catharanthus roseus

D Thakore, AK Srivastava, AK Sinha - Biochemical Engineering Journal, 2017 - Elsevier
Catharanthus roseus has been known to produce Ajmalicine which is used for treatment of
circulatory disorders. Significantly low content of the drug in the natural plant necessitates …

[HTML][HTML] Production of tropane alkaloids in Hyoscyamus niger (black henbane) hairy roots grown in bubble-column and spray bioreactors

Z Jaremicz, M Luczkiewicz, A Kokotkiewicz… - Biotechnology …, 2014 - Springer
Hairy root cultures of Hyoscyamus niger were cultivated in shake-flasks, a bubble-column
bioreactor and a hybrid bubble-column/spray bioreactor and evaluated for alkaloid …

Artemisinin production by plant hairy root cultures in gas-and liquid-phase bioreactors

N Patra, AK Srivastava - Plant cell reports, 2016 - Springer
Key message Alternative biotechnological protocol for large-scale artemisinin production
was established. It featured enhanced growth and artemisinin production by cultivation of …

Agrobacterium rhizogenes-Mediated Transformation in Medicinal Plants: Prospects and Challenges

D Roychowdhury, A Majumder, S Jha - Biotechnology for medicinal plants …, 2012 - Springer
A large number of plant species from several families have been successfully transformed
by Agrobacterium rhizogenes and established in culture. In contrast to normal roots, the Ri …