Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …

Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

Osteoporosis (OP) is characterized by decreased trabecular bone volume and
microarchitectural deterioration in the medullary cavity. Urolithin A (UA) is a biologically …

Periodontal disease is a multifactorial, bacterially induced inflammatory condition
characterized by the progressive destruction of periodontal tissues. The successful …

Background Wear particles-induced osteolysis is a major long-term complication after total
joint arthroplasty. Up to now, there is no effective treatment for wear particles-induced …

Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …

Periodontitis is a prevalent chronic disease that results in loss of periodontal ligament and
bone resorption. Triggered by pathogens and prolonged inflammation, periodontitis is …

Cadmium (Cd) is a widespread environmental and industrial pollutant to cause various bone
metabolic diseases. Our former study reported that Cd promoted adipogenesis and inhibited …

Periodontitis is an inflammatory disease caused by bacterial infection directly, and the
dysregulation of host immune-inflammatory response finally destroys periodontal tissues …

Periodontitis is a chronic inflammatory disease associated with a dysbiotic bacterial biofilm
in the subgingival environment that may disturb the balance between the oral microbiome …