Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …

NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …

Osteoarthritis (OA) is the most common chronic disease of human joints. The basis of
pathologic changes involves all the tissues forming the joint; already, at an early stage, it has …

The skeleton is an exquisitely sensitive and archetypal T3-target tissue that demonstrates
the critical role for thyroid hormones during development, linear growth, and adult bone …

Abstract Nuclear Factor Kappa-Β (NF-kB) is recognized as one of the main inflammatory
pathways in the Autoimmune Disease (AD) Rheumatoid Arthritis (RA), which exhibits high …

Osteoarthritis (OA) is a rheumatic disease leading to chronic pain and disability with no
effective treatment available. Recently, allogeneic human mesenchymal stromal/stem cells …

An autoimmune disease is defined as a clinical syndrome resulted from an instigation of
both T cell and B cell or individually, in the absence of any present infection or any sort of …

Effective treatment of osteoarthritis (OA) remains a huge clinical challenge despite major
research efforts. Different tissues and cell-types within the joint contribute to disease …

The objective was to investigate the effect of kinsenoside (Kin) treatments on macrophage
polarity and evaluate the resulting protection of chondrocytes to attenuate osteoarthritis (OA) …

Osteoarthritis (OA) is associated with cartilage destruction, subchondral bone remodeling
and inflammation of the synovial membrane, although the etiology and pathogenesis …