T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity
SA Sagan, Z Moinfar, CE Moseley… - Proceedings of the …, 2023 - National Acad Sciences
Aquaporin-4 (AQP4)-specific Th17 cells are thought to have a central role in neuromyelitis
optica (NMO) pathogenesis. When modeling NMO, only AQP4-reactive Th17 cells from …
optica (NMO) pathogenesis. When modeling NMO, only AQP4-reactive Th17 cells from …
In vivo behavior of systemically administered encapsulin protein nanocages and implications for their use in targeted drug delivery
Encapsulins, self‐assembling protein nanocages derived from prokaryotes, are promising
nanoparticle‐based drug delivery systems (NDDS). However, the in vivo behavior and fate …
nanoparticle‐based drug delivery systems (NDDS). However, the in vivo behavior and fate …
The good and the bad of T cell cross-reactivity: challenges and opportunities for novel therapeutics in autoimmunity and cancer
C Gouttefangeas, R Klein, A Maia - Frontiers in Immunology, 2023 - frontiersin.org
T cells are main actors of the immune system with an essential role in protection against
pathogens and cancer. The molecular key event involved in this absolutely central task is …
pathogens and cancer. The molecular key event involved in this absolutely central task is …
From proteome to candidate vaccines: target discovery and molecular dynamics-guided multi-epitope vaccine engineering against kissing bug
Introduction Trypanosoma cruzi is a protozoan parasite that causes the tropical ailment
known as Chagas disease, which has its origins in South America. Globally, it has a major …
known as Chagas disease, which has its origins in South America. Globally, it has a major …
A Stacking Machine Learning Method for IL-10-Induced Peptide Sequence Recognition Based on Unified Deep Representation Learning
J Li, J Jiang, H Pei, Z Lv - Applied Sciences, 2023 - mdpi.com
Interleukin-10 (IL-10) has anti-inflammatory properties and is a crucial cytokine in regulating
immunity. The identification of IL-10 through wet laboratory experiments is costly and time …
immunity. The identification of IL-10 through wet laboratory experiments is costly and time …
基于幽门螺杆菌hp0169 基因三维结构的生物信息学分析.
林玲辉， 李娜， 尹晓燕， 王晓凌… - Journal of Jilin …, 2024 - search.ebscohost.com
目的: 克隆幽门螺杆菌(Hp) hp0169 基因并进行晶体学研究, 分析其二级结构和三维结构. 方法:
由UniProt 数据库中检索Hp NCTC26695 菌株hp0169 基因及其编码蛋白序列 …
由UniProt 数据库中检索Hp NCTC26695 菌株hp0169 基因及其编码蛋白序列 …
In vivo fate of systemically administered encapsulin protein nanocages and implications for their use in targeted drug delivery
Encapsulins, self-assembling protein nanocages derived from prokaryotes, are promising
nanoparticle-based drug delivery systems (NDDS). However, the in vivo behavior and fate of …
nanoparticle-based drug delivery systems (NDDS). However, the in vivo behavior and fate of …
An emerging trends of bioinformatics and big data analytics in healthcare
SK Mishra, J Jeba Praba… - Digital Transformation in …, 2024 - books.google.com
In the current situation, the world is facing a variety of diseases, and healthcare
management is also facing various enabling challenges due to emerging diseases. As …
management is also facing various enabling challenges due to emerging diseases. As …
Igniting Creativity: Hackathons for Developing Undergraduate Research Projects in Antibody Engineering
S Porter, M Bryans, S Vemu, A Kamajaya… - Journal of advanced …, 2023 - par.nsf.gov
Life science organizations are increasingly using hackathons to bring communities together
to tackle shared problems, teach skills, and develop new resources. In this study, we …
to tackle shared problems, teach skills, and develop new resources. In this study, we …
Mapping Immunogenic Regions In SARS-CoV-2 to Understand Vaccine Design Using Bioinformatics
JA Sanchez Rocha, B Anderson, J Morales… - Journal of advanced …, 2023 - par.nsf.gov
Disparities in undergraduate STEM degree completions across the United States are a
national concern. Undergraduate-level research opportunities are vital for developing future …
national concern. Undergraduate-level research opportunities are vital for developing future …