Phospholipid membranes as chemically and functionally tunable materials
The sheet‐like lipid bilayer is the fundamental structural component of all cell membranes.
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …
Membrane transformations of fusion and budding
Membrane fusion and budding mediate fundamental processes like intracellular trafficking,
exocytosis, and endocytosis. Fusion is thought to open a nanometer-range pore that may …
exocytosis, and endocytosis. Fusion is thought to open a nanometer-range pore that may …
MXene/ZIF-L co-stacking membranes with high water permeation for solute-tailored selectivity
X Zhu, M Lou, J Chen, X Fang, S Huang, F Li - Applied Surface Science, 2023 - Elsevier
Herein, we design a composite MXene membrane with high permeability and stability by
introducing highly porous two-dimensional ZIF (zeolitic imidazolate framework)-L sheets. On …
introducing highly porous two-dimensional ZIF (zeolitic imidazolate framework)-L sheets. On …
Lymph Node Follicle‐Targeting STING Agonist Nanoshells Enable Single‐Shot M2e Vaccination for Broad and Durable Influenza Protection
HH Tsai, PH Huang, LCW Lin, BY Yao… - Advanced …, 2023 - Wiley Online Library
The highly conserved matrix protein 2 ectodomain (M2e) of influenza viruses presents a
compelling vaccine antigen candidate for stemming the pandemic threat of the mutation …
compelling vaccine antigen candidate for stemming the pandemic threat of the mutation …
A Membrane Tension‐Responsive Mechanosensitive DNA Nanomachine
H Zheng, H Li, M Li, T Zhai, X Xie, C Li… - Angewandte Chemie …, 2023 - Wiley Online Library
Membrane curvature reflects physical forces operating on the lipid membrane, which plays
important roles in cellular processes. Here, we design a mechanosensitive DNA (MSD) …
important roles in cellular processes. Here, we design a mechanosensitive DNA (MSD) …
Mesoscale simulation of biomembranes with FreeDTS
W Pezeshkian, JH Ipsen - Nature Communications, 2024 - nature.com
We present FreeDTS software for performing computational research on biomembranes at
the mesoscale. In this software, a membrane is represented by a dynamically triangulated …
the mesoscale. In this software, a membrane is represented by a dynamically triangulated …
Adhesion energy controls lipid binding-mediated endocytosis
R Groza, KV Schmidt, PM Müller, P Ronchi… - Nature …, 2024 - nature.com
Several bacterial toxins and viruses can deform membranes through multivalent binding to
lipids for clathrin-independent endocytosis. However, it remains unclear, how membrane …
lipids for clathrin-independent endocytosis. However, it remains unclear, how membrane …
Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS
G Yin, J Huang, J Petela, H Jiang, Y Zhang… - … and Targeted Therapy, 2023 - nature.com
Abstract Small GTPases including Ras, Rho, Rab, Arf, and Ran are omnipresent molecular
switches in regulating key cellular functions. Their dysregulation is a therapeutic target for …
switches in regulating key cellular functions. Their dysregulation is a therapeutic target for …
Shape Transformation of Polymer Vesicles
Conspectus Life activities, such as respiration, are accomplished through the continuous
shape modulation of cells, tissues, and organs. Developing smart materials with shape …
shape modulation of cells, tissues, and organs. Developing smart materials with shape …
Molecular mechanism of GTP binding-and dimerization-induced enhancement of Sar1-mediated membrane remodeling
The Sar1 GTPase initiates coat protein II (COPII)-mediated protein transport by generating
membrane curvature at subdomains on the endoplasmic reticulum, where it is activated by …
membrane curvature at subdomains on the endoplasmic reticulum, where it is activated by …