Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Biofilms are structured microbial communities attached to surfaces, which play a significant
role in the persistence of biofoulings in both medical and industrial settings. Bacteria in …

Antibiotic-resistant bacterial infections arising from acquired resistance and/or through
biofilm formation necessitate the development of innovative 'outside of the box'therapeutics …

Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

Abstract The International Working Group on the Diabetic Foot (IWGDF) has published
evidence‐based guidelines on the prevention and management of diabetic foot disease …

Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Titanium implants have been widely used in bone tissue engineering for decades. However,
orthopedic implant-associated infections increase the risk of implant failure and even lead to …

Biofilm formation is a major concern in various sectors and cause severe problems to public
health, medicine, and industry. Bacterial biofilm formation is a major persistent threat, as it …

Biofilms, present as microorganisms and surviving on surfaces, can increase food cross-
contamination, leading to changes in the food industry's cleaning and disinfection dynamics …