[HTML][HTML] Formal guidelines: management of acute respiratory distress syndrome

L Papazian, C Aubron, L Brochard, JD Chiche… - Annals of intensive …, 2019 - Springer
Fifteen recommendations and a therapeutic algorithm regarding the management of acute
respiratory distress syndrome (ARDS) at the early phase in adults are proposed. The Grade …

[HTML][HTML] Recent progress regarding kaempferol for the treatment of various diseases

JIE Ren, Y Lu, Y Qian, B Chen… - Experimental and …, 2019 - spandidos-publications.com
Kaempferol, also known as kaempferol‑3 or kaempferide, is a flavonoid compound that
naturally occurs in tea, as well as numerous common vegetables and fruits, including beans …

[HTML][HTML] Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS

C Ferrando, F Suarez-Sipmann, R Mellado-Artigas… - Intensive care …, 2020 - Springer
Purpose The main characteristics of mechanically ventilated ARDS patients affected with
COVID-19, and the adherence to lung-protective ventilation strategies are not well known …

Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial

J Villar, C Ferrando, D Martínez, A Ambrós… - The Lancet …, 2020 - thelancet.com
Background There is no proven specific pharmacological treatment for patients with the
acute respiratory distress syndrome (ARDS). The efficacy of corticosteroids in ARDS …

Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries

G Bellani, JG Laffey, T Pham, E Fan, L Brochard… - Jama, 2016 - jamanetwork.com
Importance Limited information exists about the epidemiology, recognition, management,
and outcomes of patients with the acute respiratory distress syndrome (ARDS). Objectives …

[HTML][HTML] Roles of heat shock proteins in apoptosis, oxidative stress, human inflammatory diseases, and cancer

PC Ikwegbue, P Masamba, BE Oyinloye, AP Kappo - Pharmaceuticals, 2017 - mdpi.com
Heat shock proteins (HSPs) play cytoprotective activities under pathological conditions
through the initiation of protein folding, repair, refolding of misfolded peptides, and possible …

[HTML][HTML] Asynchronies during mechanical ventilation are associated with mortality

L Blanch, A Villagra, B Sales, J Montanya… - Intensive care …, 2015 - Springer
Purpose This study aimed to assess the prevalence and time course of asynchronies during
mechanical ventilation (MV). Methods Prospective, noninterventional observational study of …

[HTML][HTML] Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

JG Laffey, G Bellani, T Pham, E Fan, F Madotto… - Intensive care …, 2016 - Springer
Purpose To improve the outcome of the acute respiratory distress syndrome (ARDS), one
needs to identify potentially modifiable factors associated with mortality. Methods The large …

Past and present ARDS mortality rates: a systematic review

J Máca, O Jor, M Holub, P Sklienka, F Burša… - Respiratory …, 2017 - rc.rcjournal.com
ARDS is severe form of respiratory failure with significant impact on the morbidity and
mortality of critical care patients. Epidemiological data are crucial for evaluating the efficacy …

[HTML][HTML] The future of mechanical ventilation: lessons from the present and the past

L Gattinoni, JJ Marini, F Collino, G Maiolo, F Rapetti… - Critical Care, 2017 - Springer
The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS)
arise from two main causes: unphysiological increases of transpulmonary pressure and …