[HTML][HTML] Squeezing for life–properties of red blood cell deformability

R Huisjes, A Bogdanova, WW Van Solinge… - Frontiers in …, 2018 - frontiersin.org
Deformability is an essential feature of blood cells (RBCs) that enables them to travel
through even the smallest capillaries of the human body. Deformability is a function of (i) …

[HTML][HTML] Advances in microfluidics for single red blood cell analysis

GV Grigorev, AV Lebedev, X Wang, X Qian… - Biosensors, 2023 - mdpi.com
The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Multifunctional surface microrollers for targeted cargo delivery in physiological blood flow

Y Alapan, U Bozuyuk, P Erkoc, AC Karacakol, M Sitti - Science robotics, 2020 - science.org
Mobile microrobots offer great promise for minimally invasive targeted medical theranostic
applications at hard-to-access regions inside the human body. The circulatory system …

Soft erythrocyte-based bacterial microswimmers for cargo delivery

Y Alapan, O Yasa, O Schauer, J Giltinan, AF Tabak… - Science robotics, 2018 - science.org
Bacteria-propelled biohybrid microswimmers have recently shown to be able to actively
transport and deliver cargos encapsulated into their synthetic constructs to specific regions …

Mobile microrobots for active therapeutic delivery

P Erkoc, IC Yasa, H Ceylan, O Yasa… - Advanced …, 2019 - Wiley Online Library
Recent advances in the versatility and sophistication of design, fabrication, and control
methods of mobile microrobots could have a transforming impact on future healthcare …

Shape-encoded dynamic assembly of mobile micromachines

Y Alapan, B Yigit, O Beker, AF Demirörs, M Sitti - Nature materials, 2019 - nature.com
Field-directed and self-propelled colloidal assembly have been used to build
micromachines capable of performing complex motions and functions. However, integrating …

Programmable collective behavior in dynamically self‐assembled mobile microrobotic swarms

B Yigit, Y Alapan, M Sitti - Advanced Science, 2019 - Wiley Online Library
Collective control of mobile microrobotic swarms is indispensable for their potential high‐
impact applications in targeted drug delivery, medical diagnostics, parallel …

Reconfigurable vortex-like paramagnetic nanoparticle swarm with upstream motility and high body-length ratio velocity

L Wang, H Gao, H Sun, Y Ji, L Song, L Jia, C Wang… - Research, 2023 - spj.science.org
Drug delivery systems with high-targeted doses can minimize excipients, reduce side
effects, and improve efficacy. Human blood circulation is a complex circulatory system, and …

Whole blood viscosity and red blood cell adhesion: Potential biomarkers for targeted and curative therapies in sickle cell disease

E Kucukal, Y Man, A Hill, S Liu, A Bode… - American journal of …, 2020 - Wiley Online Library
Sickle cell disease (SCD) is a recessive genetic blood disorder exhibiting abnormal blood
rheology. Polymerization of sickle hemoglobin, due to a point mutation in the β‐globin gene …

[HTML][HTML] iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays

ME Fay, O Oshinowo, E Iffrig, KS Fibben… - Nature …, 2023 - nature.com
While microscopy-based cellular assays, including microfluidics, have significantly
advanced over the last several decades, there has not been concurrent development of …