Artificial intelligence aids in development of nanomedicines for cancer management

P Tan, X Chen, H Zhang, Q Wei, K Luo - Seminars in cancer biology, 2023 - Elsevier
Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …

Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Integrated SERS-vertical flow biosensor enabling multiplexed quantitative profiling of serological exosomal proteins in patients for accurate breast cancer subtyping

X Su, X Liu, Y Xie, M Chen, C Zheng, H Zhong, M Li - ACS nano, 2023 - ACS Publications
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …

Nanomaterial-based microfluidic systems for cancer biomarker detection: recent applications and future perspectives

Y Xiang, C Hu, G Wu, S Xu, Y Li - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Detecting cancer biomarkers (eg, circulating tumor cells, extracellular vehicles, nucleic
acids, and protein biomarkers) is vital for risk assessment and early diagnosis. Nanomaterial …

Nanoenzymes in disease diagnosis and therapy

Z Yu, R Lou, W Pan, N Li, B Tang - Chemical Communications, 2020 - pubs.rsc.org
Nanoenzymes, as a new generation of artificial enzymes with highly effective enzyme-like
properties, have come into focus and have achieved great progress. Considering the …

Hybrid membrane-coated biomimetic nanoparticles (HM@ BNPs): a multifunctional nanomaterial for biomedical applications

Y Zhao, A Li, L Jiang, Y Gu, J Liu - Biomacromolecules, 2021 - ACS Publications
The application of nanoparticles in the diagnosis and treatment of diseases has undergone
different developmental stages, but phagocytosis and nonspecific distribution have been the …

Discovering the Secret of Diseases by Incorporated Tear Exosomes Analysis via Rapid-Isolation System: iTEARS

L Hu, T Zhang, H Ma, Y Pan, S Wang, X Liu, X Dai… - ACS …, 2022 - ACS Publications
Nanoscale small extracellular vesicles (sEVs, exosomes) in tears allow us to investigate the
multisignatures of diseases. However, the translations of tear sEVs for biomarker discovery …

The landscape of biomimetic nanovesicles in brain diseases

Q You, F Liang, G Wu, F Cao, J Liu, Z He… - Advanced …, 2024 - Wiley Online Library
Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …

Recent advances of utilizing artificial intelligence in lab on a chip for diagnosis and treatment

S Zare Harofte, M Soltani, S Siavashy, K Raahemifar - Small, 2022 - Wiley Online Library
Nowadays, artificial intelligence (AI) creates numerous promising opportunities in the life
sciences. AI methods can be significantly advantageous for analyzing the massive datasets …

Rapid capture of cancer extracellular vesicles by lipid patch microarrays

HY Liu, R Kumar, C Zhong, S Gorji… - Advanced …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) contain various bioactive molecules such as DNA, RNA, and
proteins, and play a key role in the regulation of cancer progression. Furthermore, cancer …