[HTML][HTML] Meshfree and particle methods in biomechanics: Prospects and challenges
The use of meshfree and particle methods in the field of bioengineering and biomechanics
has significantly increased. This may be attributed to their unique abilities to overcome most …
has significantly increased. This may be attributed to their unique abilities to overcome most …
Blood pressure-driven rupture of blood vessels
To develop better diagnosis and treatment techniques of cardiovascular disease such as
aneurysm, further understandings of the biomechanical mechanisms and failure behaviors …
aneurysm, further understandings of the biomechanical mechanisms and failure behaviors …
[HTML][HTML] A three-dimensional fluid-structure interaction model based on SPH and lattice-spring method for simulating complex hydroelastic problems
The present work revolves around the development of a 3D particle-based Fluid-Structure
Interaction (FSI) solver to simulate hydroelastic problems that involve free surface. The three …
Interaction (FSI) solver to simulate hydroelastic problems that involve free surface. The three …
[HTML][HTML] Fluid-structure interaction of blood flow around a vein valve
Methods: In the present work, the blood flow through a venous valve considering the
flexibility of the vein wall and valve leaflets is investigated numerically. The governing …
flexibility of the vein wall and valve leaflets is investigated numerically. The governing …
Modelling and simulation of the hydrodynamics and mixing profiles in the human proximal colon using Discrete Multiphysics
M Schütt, K Stamatopoulos, MJH Simmons… - Computers in biology …, 2020 - Elsevier
The proximal part of the colon offers opportunities to prolong the absorption window
following oral administration of a drug. In this work, we used computer simulations to …
following oral administration of a drug. In this work, we used computer simulations to …
A coupled smoothed particle hydrodynamics-volume compensated particle method (SPH-VCPM) for fluid structure interaction (FSI) modelling
A new unified particle model that couples the Smoothed Particle Hydrodynamics (SPH) and
a discontinuous approach known as the Volume Compensated Particle Method (VCPM) is …
a discontinuous approach known as the Volume Compensated Particle Method (VCPM) is …
[HTML][HTML] Simulating the hydrodynamic conditions of the human ascending colon: a digital twin of the dynamic colon model
M Schütt, C O'farrell, K Stamatopoulos, CL Hoad… - Pharmaceutics, 2022 - mdpi.com
The performance of solid oral dosage forms targeting the colon is typically evaluated using
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …
Numerical computation of fluid–solid mixture flow using the SPH–VCPM–DEM method
In this paper, a unified particle-based solver is developed to solve complex fluid–solid
mixture flow problem involving many elastic solid bodies. Our previous Fluid Structure …
mixture flow problem involving many elastic solid bodies. Our previous Fluid Structure …
Using Discrete Multi-Physics for studying the dynamics of emboli in flexible venous valves
Emboli, which are parts of blood clots, can be stuck in the vasculature of various organs
(most frequently, lungs) and cause their malfunction or even death. In this work, using …
(most frequently, lungs) and cause their malfunction or even death. In this work, using …
A fully Lagrangian formulation for fluid-structure interaction problems with free-surface flows and fracturing solids
This paper presents a novel coupled formulation for fluid-structure interaction (FSI) problems
involving free-surface fluid flows, fracture phenomena, solid mutual contact and large …
involving free-surface fluid flows, fracture phenomena, solid mutual contact and large …